Grant-in-Aid for Scientific Research on Innovative Areas

Koji Yasutomo

Koji Yasutomo

http://immunology.hosp.med.tokushima-u.ac.jp/immunology/system/top/index.php

1. Maekawa Y, Ishifune C, Tsukumo SI, Hozumi K, Yagita H, Yasutomo K.

Notch controls the survival of memory CD4+ T cells by regulating glucose uptake.

Nat. Med. 21: 55-61. 2015

2. Kitamura A, Sasaki Y, Abe T, Kano H, Yasutomo K. An inherited mutation in NLRC4 causes autoinflammation in human and mice.

J. Exp. Med. 211: 2385-96. 2014

3. Nakajima K, Maekawa Y, Kataoka K, Ishifune C, Nishida J, Arimochi H, Kitamura A, Yoshimoto T, Tomita S, Nagahiro S, Yasutomo K.

The ARNT-STAT3 axis regulates the differentiation of intestinal intraepithelial TCRαβ+CD8αα+cells.

Nat. Commun. 4: 2112. 2013

4. Kitamura A, Maekawa Y, Uehara H, Izumi K, Kawachi I, Nishizawa M, Toyoshima Y, Takahashi H, Standley DM, Tanaka K, Hamazaki J, Murata S, Obara K, Toyoshima I, Yasutomo K.

A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans.

J. Clin. Invest. 121: 4150–60. 2011

5. Maekawa Y, Minato Y, Ishifune C, Kurihara T, Kitamura A, Kojima H, Yagita H, Sakata-Yanagimoto M, Saito T, Taniuchi I, Chiba S, Sone S, Yasutomo K.

Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.

Nat. Immunol. 9: 1140-7. 2008