Murai S, Yamaguchi Y, Shirasaki Y, Yamagishi M, Shindo R, Hildebrand JM, Miura R, Nakabayashi O, Totsuka M, Tomida T, Adachi-Akahane S, Uemura S, Silke J, Yagita H, Miura M, Nakano H.

A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs.

Nat. Commun. 9: 4457, 2018.

 

Kurosawa T, Miyoshi S, Yamazaki S, Nishina T, Mikami T, Oikawa A, Homma S, Nakano H.

A murine model of acute lung injury identifies growth factors to promote tissue repair and their biomarkers.

Genes Cells  in press. 2018.

 

Deguchi Y, Nishina T, Asano K, Ohmuraya M, Nakagawa Y, Nakagata N, Sakuma T, Yamamoto T, Araki K, Mikami T, Tanaka M, Nakano H.

Generation of and characterization of anti-IL-11 antibodies using newly established Il11-deficient mice.

Biochem. Biophys. Res. Commun. 505: 453-459, 2018.

 

Piao X, Miura R, Miyake S, Komazawa-Sakon S, Koike M, Shindo R, Takeda J, Hasegawa A, Abe R, Nishiyama C, Mikami T, Yagita H, Uchiyama Y, Nakano H.

Blockade of TNF receptor superfamily 1 (TNFR1)-dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation.

J. Allergy Clin. Immunol. 2018. [Epub ahead of print]

 

Sasaki Y, Iwai K.

Crucial role of LUBAC-mediated inhibition of programmed cell death in TLR4-mediated B cell responses and B1b cell development.

J. Immunol. 200: 3438-3449, 2018.

 

Nagata M, Arakawa S, Yamaguchi H, Torii S, Endo H, Tsujioka M, Honda S, Nishida Y, Konishi A, Shimizu S.

Dram1 regulates DNA damage-induced alternative autophagy.

Cell Stress  2: 55-65, 2018.

 

Nakamura H, Kikuchi S, Kawai K, Ishii S, Sato S.

closo-Dodecaborate-conjugated human serum albumins: preparation and in vivo selective boron delivery to tumor.

Pure Appl. Chem.90, 2018.

 

Chiyonobu N, Shimada S, Akiyama Y, Mogushi K, Itoh M, Akahoshi K, Matsumura S, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Suganami T, Yamaoka S, Ogawa Y, Tanabe M, Tanaka S.

Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors.

Am. J. Pathol. 2018. [Epub ahead of print]

 

Okada H, Yamada M, Kamimoto K, Kok CY, Kaneko K, Ema M, Miyajima A, Itoh T.

The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury.

J. Biol. Chem. 2018. [Epub ahead of print]

 

Watanabe H, Inaba Y, Kimura K, Matsumoto M, Kaneko S, Kasuga M, Inoue H.

Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein.

Nat. Commun. 9: 30, 2018.

 

Yamaguchi T, Suzuki T, Sato T, Takahashi A, Watanabe H, Kadowaki A, Natsui M, Inagaki H, Arakawa S, Nakaoka S, Koizumi Y, Seki S, Adachi S, Fukao A, Fujiwara T, Natsume T, Kimura A, Komatsu M, Shimizu S, Ito H, Suzuki Y, Penninger JM, Yamamoto T, Imai Y, Kuba K.

The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.

Sci. Signal. 11: 2018.

 

Matsuda M, Tsurusaki S, Miyata N, Saijou E, Okochi H, Miyajima A, Tanaka M.

Oncostatin M causes liver fibrosis by regulating cooperation between hepatic stellate cells and macrophages in mice.

Hepatology 67: 296-312, 2018.

 

Segawa K, Kurata S, Nagata S.

The CDC50A extracellular domain is required for forming a functional complex with and chaperoning phospholipid flippases to the plasma membrane.

J. Biol. Chem. 293: 2172-2182, 2018.

 

Sakamoto S, Miyamoto T, Usui K, Tanaka H, Morimoto S.

Sodium-Periodate-Mediated Harringtonine Derivatives and Their Antiproliferative Activity against HL-60 Acute Leukemia Cells.

J. Nat. Prod. 81: 34-40, 2018.

 

Tsukumo SI, Yasutomo K.

Regulation of CD8+ T Cells and Antitumor Immunity by Notch Signaling.

Front. Immunol. 9:101, 2018. Review.

 

Fuse S, Inaba M, Sato S, Joshi M, Nakamura H.

Synthesis of Pyrazolofuropyrazine via One-pot SNAr Reaction/Intramolecular C-H Direct Arylation.

Synthesis 50:1493-8, 2018.

 

Shinde PV, Xu HC, Maney SK, Kloetgen A, Namineni S, Zhuang Y, Honke N, Shaabani N, Bellora N, Doerrenberg M, Trilling M, Pozdeev VI, van Rooijen N, Scheu S, Pfeffer K, Crocker PR, Tanaka M, Duggimpudi S, Knolle P, Heikenwalder M, Ruland J, Mak TW, Brenner D, Pandyra AA, Hoell JI, Borkhardt A, Häussinger D, Lang KS, Lang PA.

Tumor Necrosis Factor-Mediated Survival of CD169(+) Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection.

J. Virol. 92: 2018.

 

Tanaka M, Itoh M, Ogawa Y, Suganami T.

Molecular mechanism of obesity-induced ‘metabolic’ tissue remodeling.

J. Diabetes Investig. 9: 256-261, 2018.

 

Shiba K, Tsuchiya K, Komiya C, Miyachi Y, Mori K, Shimazu N, Yamaguchi S, Ogasawara N, Katoh M, Itoh M, Suganami T, Ogawa Y.

Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH.

Sci. Rep. 8: 2362. 2018.

 

Sawada M, Ohno N, Kawaguchi M, Huang SH, Hikita T, Sakurai Y, Bang Nguyen H, Quynh Thai T, Ishido Y, Yoshida Y, Nakagawa H, Uemura A, Sawamoto K.

PlexinD1 signaling controls morphological changes and migration termination in newborn neurons.

EMBO J. 37: 2018.

 

Jinnou H, Sawada M, Kawase K, Kaneko N, Herranz-Pérez V, Miyamoto T, Kawaue T, Miyata T, Tabata Y, Akaike T, García-Verdugo JM, Ajioka I, Saitoh S, Sawamoto K.

Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury.

Cell Stem Cell. 22:128-137.e9, 2018.

 

Foster AJ, Nagata M, Lu X, Lynch AT, Omahdi Z, Ishikawa E, Yamasaki S, Timmer MSM, Stocker BL.

Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine

Adjuvants. J. Med. Chem. 61: 1045-1060, 2018.

 

Ota F, Hirayama T, Kizuka Y, Yamaguchi Y, Fujinawa R, Nagata M, Ismanto HS, Lepenies B, Aretz J, Rademacher C, Seeberger PH, Angata T, Kitazume S, Yoshida K, Betsuyaku T, Kida K, Yamasaki S, Taniguchi N.

High affinity sugar ligands of C-type lectin receptor langerin.

Biochim. Biophys. Acta. 2018.

 

Kottom TJ, Hebrink DM, Jenson PE, Marsolek PL, Wüthrich M, Wang H, Klein B, Yamasaki S, Limper AH.

Dectin-2 Is a C-Type Lectin Receptor that Recognizes Pneumocystis and Participates in Innate Immune Responses.

Am. J. Respir. Cell.  Mol. Biol. 58: 232-240, 2018.

 

Ushijima T, Fujimoto N, Matsuyama S, Kan-O M, Kiyonari H, Shioi G, Kage Y, Yamasaki S, Takeya R, Sumimoto H.

The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice.

J. Biol. Chem. 293: 148-162, 2018.

 

Fuse S, Takizawa M, Matsumura K, Sato S, Okazaki S, Nakamura H.

Thiophene-based, Organic D-π-A dyes as Potent Sensitizers for Photodynamic Therapy.

Eur. J. Org. Chem. 34:5170-7, 2017.

 

Sato S, Ishii S, Nakamura H.

Development of Albumin-closo-Dodecaborate Conjugates as Boron Carriers for Neutron-Capture Therapy by Ru(bpy)3-Photocatalyzed Modification of Tyrosine.

Eur. J. Inorg. 38-39: 4406-10, 2017.

 

Tsushima M, Sato S, Nakamura H.

Selective Purification and Chemical Labeling of Target Protein on Ruthenium Photocatalyst-Immobilized Affinity Beads.

Chem. Commun. 53:4838-41, 2017.

 

Arai Y, Takahashi D, Asano K, Tanaka M, Oda M, Ko SBH, Ko MSH, Mandai S, Nomura N, Rai T, Uchida S, Sohara E.

Salt suppresses IFNg inducible chemokines through the IFNγ-JAK1-STAT1 signaling pathway in proximal tubular cells.

Sci. Rep. 7:46580, 2017.

 

Li Q, Wang D, Hao S, Han X, Xia Y, Li X, Chen Y, Tanaka M, Qiu CH.

CD169 Expressing Macrophage, a Key Subset in Mesenteric Lymph Nodes Promotes Mucosal Inflammation in Dextran Sulfate Sodium-Induced Colitis.

Front Immunol. 8: 669, 2017.

 

Perez OA, Yeung ST, Vera-Licona P, Romagnoli PA, Samji T, Ural B.B, Maher L, Tanaka M, Khanna KM.

CD169+ macrophages orchestrate innate immune responses by regulating bacterial localization in the spleen.

Sci. Immunol. 2, 2017.

 

Wang D, Li Q, Yang Y, Hao S, Han X, Song J, Yin Y, Li X, Tanaka M, Qiu CH.

Macrophage Subset Expressing CD169 in Peritoneal Cavity-Regulated Mucosal Inflammation Together with Lower Levels of CCL22.

Inflammation 40: 1191-1203, 2017.

 

Yotsumoto S, Muroi Y, Chiba T, Ohmura R, Yoneyama M, Magarisawa M, Dodo K, Terayama N, Sodeoka M, Aoyagi R, Arita M, Arakawa S, Shimizu S, Tanaka M.

Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation.

Sci. Rep. 7: 16026, 2017.

 

Kamatani T, Fukunaga K, Miyata K, Shirasaki Y, Tanaka J, Baba R, Matsusaka M, Kamatani N, Moro K, Betsuyaku T, Uemura S.

Construction of a system using a deep learning algorithm to count cell numbers in nanoliter wells for viable single-cell experiments.

Sci. Rep. 7: 16831, 2017.

 

Akaike T, Ida T, Wei FY, Nishida M, Kumagai Y, Alam MM, Ihara H, Sawa T, Matsunaga T, Kasamatsu S, Nishimura A, Morita M, Tomizawa K, Nishimura A, Watanabe S, Inaba K, Shima H, Tanuma N, Jung M, Fujii S, Watanabe Y, Ohmuraya M, Nagy P, Feelisch M, Fukuto JM, Motohashi H.

Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics.

Nat. Commun. 8: 1177, 2017.

 

Taki K, Hashimoto D, Nakagawa S, Ozaki N, Tomiyasu S, Ohmuraya M, Arima K, Kaida T, Higashi T, Sakamoto K, Sakata K, Okabe H, Nitta H, Hayashi H, Chikamoto A, Beppu T, Takamori H, Hirota M, Baba H.

Significance of lymph node metastasis in pancreatic neuroendocrine tumor.

Surg. Today 47: 1104-1110, 2017.

 

Itoh M, Suganami T, Kato H, Kanai S, Shirakawa I, Sakai T, Goto T, Asakawa M, Hidaka I, Sakugawa H, Ohnishi K, Komohara Y, Asano K, Sakaida I, Tanaka M, Ogawa Y.

CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis.

JCI Insight. 2: 2017.

 

Matsumoto A, Tanaka M, Matsumoto H, Ochi K, Moro-Oka Y, Kuwata H, Yamada H, Shirakawa I, Miyazawa T, Ishii H, Kataoka K, Ogawa Y, Miyahara Y, Suganami T.

Synthetic “smart gel” provides glucose-responsive insulin delivery in diabetic mice.

Sci. Adv. 3: eaaq0723, 2017.

 

Nakajima A, Nakatani A, Hasegawa S, Irie J, Ozawa K, Tsujimoto G, Suganami T, Itoh H, Kimura I.

The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages.

PLoS One 12: e0179696, 2017.

 

Takahashi D, Mori T, Sohara E, Tanaka M, Chiga M, Inoue Y, Nomura N, Zeniya M, Ochi H, Takeda S, Suganami T, Rai T, Uchida S.

WNK4 is an Adipogenic Factor and Its Deletion Reduces Diet-Induced Obesity in Mice.

E BioMedicine 18: 118-127, 2017.

 

Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, Miyachi Y, Shiba K, Yamaguchi S, Ikeda K, Ochi K, Nakabayashi K, Hata KI, Itoh M,

Suganami T, Ogawa Y.

Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis.

Sci. Rep. 7: 44754, 2017

 

Choudhary B, Kamak M, Ratnakaran N, Kumar J, Awasthi A, Li C, Nguyen K, Matsumoto K, Hisamoto N, Koushika SP.

UNC-16/JIP3 regulates early events in synaptic vesicle protein trafficking via LRK-1/LRRK2 and AP complexes.

PLoS Genet. 13: e1007100, 2017.

 

Hisamoto N, Matsumoto K.

Signal transduction cascades in axon regeneration: insights from C. elegans.

Curr. Opin. Genet. Dev. 44: 54-60, 2017.

 

Pastuhov SI, Shimizu T, Hisamoto N.

Heavy Metal Stress Assay of Caenorhabditis elegans.

Bio-protocol 7: 2312, 2017.

 

Takagishi M, Sawada M, Ohata S, Asai N, Enomoto A, Takahashi K, Weng L, Ushida K, Ara H, Matsui S, Kaibuchi K, Sawamoto K, Takahashi M.

Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus.

Cell Rep. 20: 960-972, 2017.

 

Cebrián-Silla A, Alfaro-Cervelló C, Herranz-Pérez V, Kaneko N, Park DH, Sawamoto K, Alvarez-Buylla A, Lim DA, García-Verdugo JM.

Unique Organization of the Nuclear Envelope in the Post-natal Quiescent Neural Stem Cells.

Stem Cell Reports 9: 203-216, 2017.

 

Oshikawa M, Okada K, Kaneko N, Sawamoto K, Ajioka I.

Affinity-Immobilization of VEGF on Laminin Porous Sponge Enhances Angiogenesis in the Ischemic Brain.

Adv. Healthc Mater. 6: 2017. 

 

Kaneko N, Sawada M, Sawamoto K.

Mechanisms of neuronal migration in the adult brain.

J. Neurochem. 141: 835-847, 2017.

 

Fujioka T, Kaneko N, Ajioka I, Nakaguchi K, Omata T, Ohba H, Fässler R, García-Verdugo JM, Sekiguchi K, Matsukawa N, Sawamoto K.

β1 integrin signaling promotes neuronal migration along vascular scaffolds in the post-stroke brain.

EBioMedicine 16:195-203, 2017.

 

Saito Y, Respatika D, Komori S, Washio K, Nishimura T, Kotani T, Murata Y, Okazawa H, Ohnishi H, Kaneko Y, Yui K, Yasutomo K, Nishigori C, Nojima Y, Matozaki T.

SIRPα+ dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF receptor ligands in the adult spleen.

Proc. Natl. Acad. Sci. USA 114: E10151-E10160, 2017.

 

Ikeda K, Kinoshita M, Kayama H, Nagamori S, Kongpracha P, Umemoto E, Okumura R, Kurakawa T, Murakami M, Mikami N, Shintani Y, Ueno S, Andou A, Ito M, Tsumura H, Yasutomo K, Ozono K, Takashima S, Sakaguchi S, Kanai Y, Takeda K.

Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells.

Cell Rep. 21: 1824-1838, 2017.

 

Ikeda K, Kinoshita M, Kayama H, Nagamori S, Kongpracha P, Umemoto E, Okumura R, Kurakawa T, Murakami M, Mikami N, Shintani Y, Ueno S, Andou A, Ito M, Tsumura H, Yasutomo K, Ozono K, Takashima S, Sakaguchi S, Kanai Y, Takeda K.

Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by Regulating Aldh1a2 Expression.

J. Immunol. 199: 1989-1997, 2017.

 

Niki M, Nakajima K, Ishikawa D, Nishida J, Ishifune C, Tsukumo SI, Shimada M, Nagahiro S, Mitamura Y, Yasutomo K.

MicroRNA-449a deficiency promotes colon carcinogenesis.

Sci. Rep. 7: 10696, 2017.

 

Katsumata LW, Miyajima A, Itoh T.

Portal fibroblasts marked by the surface antigen Thy1 contribute to fibrosis in mouse models of cholestatic liver injury.

Hepatol. Commun. 1: 198-214, 2017.

 

Miyamura N, Hata S, Itoh T, Tanaka M, Nishio M, Itoh M, Ogawa Y, Terai S, Sakaida I, Suzuki A, Miyajima A, Nishina H.

YAP determines the cell fate of injured mouse hepatocytes in vivo.

Nat. Commun. 8:16017, 2017.

 

Hu Y, Duan Y, Takeuchi A, Hai-Kurahara L, Ichikawa J, Hiraishi K, Numata T, Ohara H, Iribe G, Nakaya M, Mori MX, Matsuoka S, Ma G, Inoue R.

Uncovering the arrhythmogenic potential of TRPM4 activation in atrial-derived HL-1 cells using novel recording and numerical approaches.

Cardiovasc. Res. 113: 1243-1255, 2017.

 

Nagasaka A, Mogi C, Ono H, Nishi T, Horii Y, Ohba Y, Sato K, Nakaya M, Okajima F, Kurose H.

The proton-sensing G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) shows cardioprotective effects against myocardial infarction.

Sci. Rep. 7: 7812, 2017.

 

Iribe G, Kaihara K, Yamaguchi Y, Nakaya M, Inoue R, Naruse K.

Mechano-sensitivity of mitochondrial function in mouse cardiac myocytes.

Prog. Biophys. Mol. Biol. 130(Pt B):315-322, 2017.

 

Takeda T, Komiya Y, Koga T, Ishida T, Ishii Y, Kikuta Y, Nakaya M, Kurose H, Yokomizo T, Shimizu T, Uchi H, Furue M, Yamada H.

Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration.

J. Biol. Chem. 292: 10586-10599, 2017.

 

Chaikuad A, Filippakopoulos P, Marcsisin SR, Picaud S, Schröder M, Sekine S, Ichijo H, Engen JR, Takeda K, Knapp S.

Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly.

Structure 25:1089-1099.e3, 2017.

 

Kamiyama M, Shirai T, Tamura S, Suzuki-Inoue K, Ehata S, Takahashi K, Miyazono K, Hayakawa Y, Sato T, Takeda K, Naguro I, Ichijo H.

ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.

Cell Death Differ. 24: 2066-2076, 2017.

 

Tanimura S, Takeda K.

ERK signalling as a regulator of cell motility.

J. Biochem. 162:145-154. 2017. Review.

 

Konagaya Y, Terai K, Hirao Y, Takakura K, Imajo M, Kamioka Y, Sasaoka N, Kakizuka A, Sumiyama K, Asano T, Matsuda M.

A Highly Sensitive FRET Biosensor for AMPK Exhibits Heterogeneous AMPK Responses among Cells and Organs.

Cell Rep. 21:2628-2638, 2017.

 

Hiratsuka T, Sano T, Kato H, Komatsu N, Imajo M, Kamioka Y, Sumiyama K, Banno F, Miyata T, Matsuda M

Live imaging of extracellular signal-regulated kinase and protein kinase A activities during thrombus formation in mice expressing biosensors based on Förster　resonance energy transfer.

J. Thromb. Haemost. 15:1487-1499, 2017.

 

Mi-Ichi F, Miyamoto T, Yoshida H.

Uniqueness of Entamoeba sulfur metabolism: sulfolipid metabolism that plays pleiotropic roles in the parasitic life cycle.

Mol. Microbiol. 106: 479-491, 2017.

 

Tchegnitegni BT, Teponno RB, Jenett-Siems K, Melzig MF, Miyamoto T, Tapondjou LA.

A dihydrochalcone derivative and further steroidal saponins from Sansevieria trifasciata Prain.

Z Naturforsch C. 72: 477-482, 2017.

 

Rengifo Carrillo M, Mitaine-Offer AC, Miyamoto T, Tanaka C, Pouységu L, Quideau S, Rojas LB, Rosquete Porcar C, Lacaille-Dubois MA.

Oleanane-type glycosides from Pittosporum tenuifolium “variegatum” and P. tenuifolium “gold star”.

Phytochemistry 140:166-173, 2017.

 

Paudel MK, Sakamoto S, Van Huy L, Tanaka H, Miyamoto T, Morimoto S.

The effect of varying the peptide linker length in a single chain variable fragment antibody against wogonin glucuronide.

J. Biotechnol. 251: 47-52, 2017.

 

Paudel MK, Sakamoto S, Huy LV, Tanaka H, Miyamoto T, Takano A, Morimoto S.

Development of an immunoassay using an anti-wogonin glucuronide monoclonal antibody.

J. Immunoassay Immunochem. 38: 457-470, 2017.

 

Sakamoto T, Imai H.

Hydrogen peroxide produced by superoxide dismutase SOD-2 activates sperm in Caenorhabditis elegans.

J. Biol. Chem. 292:14804-14813, 2017.

 

Imai H, Matsuoka M, Kumagai T, Sakamoto T, Koumura T.

Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis.

Curr. Top. Microbiol. Immunol. 403: 143-170. 2017. Review.

 

Sakai O, Yasuzawa T, Sumikawa Y, Ueta T, Imai H, Sawabe A, Ueshima S.

Role of GPx4 in human vascular endothelial cells, and the compensatory activity of brown rice on GPx4 ablation condition.

Pathophysiology 24: 9-15, 2017.

 

Uchida T, Sakai O, Imai H, Ueta T.

Role of Glutathione Peroxidase 4 in Corneal Endothelial Cells.

Curr. Eye Res. 42: 380-385, 2017.

 

Yanagihashi Y, Segawa K, Maeda R, Nabeshima YI, Nagata S.

Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis.

Proc. Natl. Acad. Sci. USA 114: 8800-8805, 2017.

 

Gyobu S, Ishihara K, Suzuki J, Segawa K, Nagata S.

Characterization of the scrambling domain of the TMEM16 family.

Proc. Natl. Acad. Sci. USA 114: 6274-6279, 2017.

 

Yotsumoto S, Muroi Y, Chiba T, Ohmura R, Yoneyama M, Magarisawa M, Dodo K, Terayama N, Sodeoka M, Aoyagi R, Arita M, Arakawa S, Shimizu S, Tanaka M.

Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation.

Sci. Rep. 7:16026, 2017.

 

Arakawa S, Tsujioka M, Yoshida T, Tajima-Sakurai H, Nishida Y, Matsuoka Y, Yoshino I, Tsujimoto Y, Shimizu S.

Role of Atg5-dependent cell death in the embryonic development of Bax/Bak double-knockout mice.

Cell Death Differ. 24:1598-1608, 2017.

 

Arakawa S, Honda S, Torii S, Tsujioka M, Shimizu S.

Monitoring of Atg5-Independent Mitophagy.

Methods Mol Biol. 1-8, 2017. Review

 

Arakawa S, Honda S, Yamaguchi H, Shimizu S.

Molecular mechanisms and physiological roles of Atg5/Atg7-independent alternative autophagy.

Proc. Jpn. Acad. Ser. B Phys. Biol. Sci. 93: 378-385. 2017. Review.

 

Shinjo Y, Makide K, Satoh K, Fukami F, Inoue A, Kano K, Otani Y, Ohwada T, Aoki J.

Lysophosphatidylserine suppresses IL-2 production in CD4 T cells through LPS3/GPR174.

Biochem. Biophys. Res. Commun. 494: 332-338, 2017.

 

Aikawa S, Kano K, Inoue A, Wang J, Saigusa D, Nagamatsu T, Hirota Y, Fujii T, Tsuchiya S, Taketomi Y, Sugimoto Y, Murakami M, Arita M, Kurano M, Ikeda H, Yatomi Y, Chun J, Aoki J.

Autotaxin-lysophosphatidic acid-LPA₃ signaling at the embryo-epithelial boundary controls decidualization pathways.

EMBO J. 36: 2146-2160, 2017.

 

Kondo T, Morita R, Okuzono Y, Nakatsukasa H, Sekiya T, Chikuma S, Shichita T, Kanamori M, Kubo M, Koga K, Miyazaki T, Kassai Y, Yoshimura A.

Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy.

Nat. Commun. 8:15338, 2017.

 

Shichita T, Ito M, Morita R, Komai K, Noguchi Y, Ooboshi H, Koshida R, Takahashi S, Kodama T, Yoshimura A.

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1.

Nat. Med. 23: 723-732, 2017.

 

Komai K, Shichita T, Ito M, Kanamori M, Chikuma S, Yoshimura A.

Role of scavenger receptors as damage-associated molecular pattern receptors in Toll-like receptor activation.

Int. Immunol. 29: 59-70, 2017.

 

Miyamura N, Hata S, Itoh T, Tanaka M, Nishio M, Itoh M, Ogawa Y, Terai S, Sakaida I, Suzuki A, Miyajima A, Nishina H.

YAP determines the cell fate of injured mouse hepatocytes in vivo.

Nat. Commun. 8: 16017, 2017.

 

Choi TY, Khaliq M, Tsurusaki S, Ninov N, Stainier DYR, Tanaka M, Shin D.

Bone morphogenetic protein signaling governs biliary-driven liver regeneration in zebrafish through tbx2b and id2a.

Hepatology 66: 1616-1630, 2017.

 

Oka M, Hashimoto K, Yamaguchi Y, Saitoh SI, Sugiura Y, Motoi Y, Honda K, Kikko Y, Ohata S, Suematsu M, Miura M, Miyake K, Katada T, Kontani K.

Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos.

J. Cell Sci. 130:3568-3577, 2017.

 

Yamaguchi Y, Miyazawa H, Miura M.

Neural tube closure and embryonic metabolism.

Congenit Anom (Kyoto) 57:134-137. 2017. Review.

 

Onogi Y, Wada T, Kamiya C, Inata K, Matsuzawa T, Inaba Y, Kimura K, Inoue H, Yamamoto S, Ishii Y, Koya D, Tsuneki H, Sasahara M, Sasaoka T.

PDGFRβ Regulates Adipose Tissue Expansion and Glucose Metabolism via Vascular Remodeling in Diet-Induced Obesity.

Diabetes. 66:1008-1021, 2017.

 

Watanabe H, Inaba Y, Kimura K, Asahara SI, Kido Y, Matsumoto M, Motoyama T, Tachibana N, Kaneko S, Kohno M, Inoue H.

Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-Induced, Nonalcoholic Fatty Liver Disease.

J. Nutr. 147: 52-60, 2017.

 

Takano T, Motozono C, Imai T, Sonoda KH, Nakanishi Y, Yamasaki S.

Dectin-1 intracellular domain determines species-specific ligand spectrum by modulating receptor sensitivity.

J. Biol. Chem. 292: 16933-16941, 2017.

 

Sato K, Omahdi Z, Shibata K, Sonoda KH, Yamasaki S, Tanaka H.

Synthesis and Biological Evaluation of O-Methylated Glycolipids Related to PGLs via Direct Stereoselective Glycosidation and Sequential Suzuki-Miyaura Coupling using Boracyclane.

Chemistry 23:16374-16379, 2017.

 

Shiokawa M, Lu X, Miyake Y, Ishikawa E, Pagès G, Pouysségur J, Ogata M, Yamasaki S.

Spontaneous chondroma formation in CD2-Cre-driven Erk-deficient mice.

Int. Immunol. 29:479-485, 2017.

 

Shiokawa M, Yamasaki S, Saijo S.

C-type lectin receptors in anti-fungal immunity.

Curr. Opin. Microbiol. 40: 123-130, 2017.

 

Yamazaki S, Tanaka Y, Araki H, Kohda A, Sanematsu F, Arasaki T, Duan X, Miura F, Katagiri T, Shindo R, Nakano H, Ito T, Fukui Y, Endo S, Sumimoto H.

The AP-1 transcription factor JunB is required for Th17 cell differentiation.

Sci Rep. 7:17402. 2017

 

Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, Tanaka K, Takahashi H, Sawasaki T, Inoue S, Oshiumi H, Seya T, Nakano H, Tanaka Y, Iwai K, Inoue J.

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polybiquitin Chains.

PLoS Pathog. 13:e1006162. 2017

 

Nishina T, Deguchi Y, Miura R, Yamazaki S, Shinkai Y, Kojima Y, Okumura K, Kumagai Y, Nakano H.

Critical contribution of NRF2 to an electrophile-induced interleukin-11 production.

J. Biol. Chem. 292: 205-16, 2017

 

Piao X, Yamazaki S, Komazawa-Sakon S, Miyake S, Nakabayashi O, Kurosawa K, Mikami T, Tanaka M, Van Rooijen N, Ohmuraya M, Oikawa A, Kojima Y, Kakuta S, Uchiyama Y, Tanaka M, Nakano H.

Depletion of myeloid cells exacerbates hepatitis and induces an aberrant increase in histone H3 in mouse serum.

Hepatology 65: 237-52, 2017

 

Nagata S, Tanaka M.

Programmed cell death and the immune system.

Nat. Rev. Immunol. 17: 333-340. 2017

 

Nakano H, Piao X, Shindo R, Komazawa-Sakon S.

Cellular FLICE-Inhibitory Protein Regulates Tissue Homeostasis.

Curr. Top Microbiol Immunol. 403:119-41. 2017

 

Yagai T, Matsui S, Harada K, Inagaki FF, Saijou E, Miura Y, Nakanuma Y, Miyajima A, Tanaka M.

Expression and localization of sterile alpha motif domain containing 5 is associated with cell type and malignancy of biliary tree.

PLoS One. 12: e0175355. 2017.

 

Miyazawa H, Yamaguchi Y*, Sugiura Y, Honda K, Kondo K, Matsuda F, Yamamoto T, Suematsu M, Miura M*. *Co-corresponding Author.

Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching.

Development 144: 63-73. 2017

 

Yagi T, Hashimoto D, Taki K, Yamamura K, Chikamoto A, Ohmuraya M, Beppu T, Baba H.

Surgery for metastatic tumors of the pancreas.

Surg. Case Rep. 3: 31. 2017

 

Kato Y, Furusyo N, Tanaka Y, Ueyama T, Yamasaki S, Murata M, Hayashi J.

The Relation between Serum Endostatin Level and Carotid Atherosclerosis in Healthy Residents of Japan: Results from the Kyushu and Okinawa Population

Study (KOPS).

Atheroscler. Thromb.  Apr 20. 2017.

 

Nagata M, Izumi Y, Ishikawa E, Kiyotake R, Doi R, Iwai S, Omahdi Z, Yamaji T, Miyamoto T, Bamba T, Yamasaki S.

Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity.

Proc. Natl. Acad. Sci. USA. 114: E3285-E3294. 2017

 

Kottom TJ, Hebrink DM, Jenson PE, Nandakumar V, Wüthrich M, Wang H, Klein B, Yamasaki S, Lepenies B, Limper AH.

The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense against Infection.

J. Immunol. 198: 3515-25. 2017

 

Mori D, Shibata K, Yamasaki S.

C-Type Lectin Receptor Dectin-2 Binds to an Endogenous Protein β-Glucuronidase on Dendritic Cells.

PLoS One 12: e0169562. 2017

 

Ishikawa E, Mori D, Yamasaki S.

Recognition of Mycobacterial Lipids by Immune Receptors.

Trends Immunol. 38:66-76. 2017

 

Ishimoto T, Ninomiya K, Inoue R, Koike M, Uchiyama Y, Mori H.

Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain.

Glia. 65: 727-39. 2017

 

Niizeki H, Hayashi R, Naiki Y, Yoshida K, Tanaka R, Shimizu A, Terashima H, Isogawa N, Abe R, Shimomura Y.

Delayed-onset heat intolerance in a Japanese patient with X-linked hypohidrotic ectodermal dysplasia associated with a large deletion involving four genes.

J. Dermatol. Apr 26. 2017

 

Sato K, Shinkuma S, Fujimoto K, Hatanaka KC, Ujiie H, Nomura T, Fujita Y, Abe R, Matsuno Y, Shimizu H.

Late-onset skin involvement on the forehead in multicentric Castleman disease.

Int. J. Dermatol. Feb 27. 2017

 

Kabata Y, Shimomura Y, Matsuo Y, Fujiwara H, Abe R.

Photodynamic therapy with intradermal application of 5-aminolevulinic acid successfully improved tumor lesions of mycosis fungoides.

Int. J. Dermatol. 56: e81-e82. 2017

 

Ujiie I, Fujita Y, Nakayama C, Matsumura W, Suzuki S, Shinkuma S, Nomura T, Abe R, Shimizu H.

Altered balance of epidermis-related chemokines in epidermolysis bullosa.

J. Dermatol. Sci. 86:37-45. 2017

 

Deguchi T, Shimomura Y, Hayashi R, Orime M, Tomiyama K, Abe R.

Cross-reactivity of cephalosporins: allergic immediate hypersensitivity to ceftriaxone in a cefcapene pivoxil-sensitized patient.

Eur. J. Dermatol. 27:187-9. 2017

 

Orime M, Tomiyama K, Hashidate H, Yoshida S, Hokari S, Tsuda A, Yokoyama H, Narita JI, Uchida Y, Kanekura T, Abe R, Ishii N, Hashimoto T, Kawai K.

Non-paraneoplastic autoimmune subepidermal bullous disease associated with fatal bronchiolitis obliterans.

J. Dermatol. 44: 461-4. 2017

 

Tomii K, Shimomura Y, Fujikawa H, Kariya N, Abe R.

Case of infantile digital fibromatosis: Observation of its dermoscopic features.

J. Dermatol. 44: 549-51. 2017

 

Hayashi R, Yoshida K, Abe R, Niizeki H, Shimomura Y.

First Japanese case of congenital generalized hypertrichosis with a copy number variation on chromosome 17q24.

J. Dermatol. Sci. 85:63-5. 2017

 

Kibune N, Shimomura Y, Hasegawa A, Saeki T, Umemori Y, Abe R.

Beneficial effect of hydroxychloroquine on cutaneous vasculitis in a Japanese patient with systemic lupus erythematosus.

J. Dermatol. 44: e52-e53. 2017

 

Ansai O, Fujikawa H, Shimomura Y, Abe R.

Case of severe acneiform eruptions associated with the BRAF inhibitor vemurafenib.

J. Dermatol. 44: e15-e16. 2017

 

Yoshimoto N, Shinkuma S, Ujiie H, Nomura T, Fujita Y, Abe R, Shimizu H.

Hypertrophic lupus erythematosus successfully treated with hydroxychloroquine.

J. Dermatol. 44:e48-e49. 2017

 

Shibagaki S, Tahara-Hanaoka S, Hiroyama T, Nakamura Y, Shibuya A.

Long-term survival of the mouse ES cell-derived mast cell, MEDMC-BRC6, in mast cell-deficient Kitw-sh/w-sh mice.

Int. Immunol. Apr 18. 2017

 

Eri T, Kawahata K, Kanzaki T, Imamura M, Michishita K, Akahira L, Bannai E, Yoshikawa N, Kimura Y, Satoh T, Uematsu S, Tanaka H, Yamamoto K.

Intestinal microbiota link lymphopenia to murine autoimmunity via PD-1₊CXCR5_-/dim B-helper T cell induction.

Sci. Rep. 7: 46037. 2017

 

Ansai O, Shimomura Y, Fujimoto A, Sakai A, Tsuchida Y, Hayashi R, Shigehara Y, Hama N, Abe R.

Case of pemphigus herpetiformis with immunoglobulin G autoantibodies against desmocollin-3.

J. Dermatol. 44: 104-5. 2017

 

Kawano Y, Fukui C, Shinohara M, Wakahashi K, Ishii S, Suzuki T, Sato M, Asada N, Kawano H, Minagawa K, Sada A, Furuyashiki T, Uematsu S, Akira S, Uede T, Narumiya S, Matsui T, Katayama Y.

G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE2.

Blood 129:587-97. 2017

 

Fukushima T, Yoshihara H, Furuta H, Hakuno F, Iemura SI, Natsume T, Nakatsu Y, Kamata H, Asano T, Komada M, Takahashi SI.

USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.

Biochem. Biophys. Res. Commun. 484: 522-8. 2017

 

Hattori T, Kaji M, Ishii H, Jureepon R, Takarada-Iemata M, Minh Ta H, Manh Le T, Konno A, Hirai H, Shiraishi Y, Ozaki N, Yamamoto Y, Okamoto H, Yokoyama S, Higashida H, Kitao Y, Hori O.

CD38 positively regulates postnatal development of astrocytes cell-autonomously and oligodendrocytes non-cell-autonomously.

Glia. 65:974-89. 2017

 

Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, Takeuchi O, Kawai T, Shimizu S, Matsuura Y, Akira S, Saitoh T.

Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response.

Proc. Natl. Acad. Sci. USA. 114: 2681-6. 2017

 

Ori D, Murase M, Kawai T.

Cytosolic nucleic acid sensors and innate immune regulation.

Int. Rev. Immunol. 36: 74-88. 2017

 

Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, Takeuchi O, Kawai T, Shimizu S, Matsuura Y, Akira S, Saitoh T.

Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response.

Proc. Natl. Acad. Sci. USA. 114: 2681-6. 2017

 

Kitai Y, Kawasaki T, Sueyoshi T, Kobiyama K, Ishii KJ, Zou J, Akira S, Matsuda T, Kawai T.

DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity.

J. Immunol. 198: 1649-59. 2017

 

Sakamoto S, Nagamitsu R, Yusakul G, Miyamoto T, Tanaka H, Morimoto S.

Ultrasensitive immunoassay for monocrotaline using monoclonal antibody produced by N, N’-carbonyldiimidazole mediated hapten-carrier protein conjugates.

Talanta 168: 67-72. 2017

 

Sakamoto S, Yusakul G, Tsuneura Y, Putalun W, Usui K, Miyamoto T, Tanaka H, Morimoto S.

Sodium periodate-mediated conjugation of harringtonine enabling the production of a highly specific monoclonal antibody, and the development of a sensitive quantitative analysis method.

Analyst 142: 1140-8. 2017

 

Sakamoto S, Yusakul G, Nuntawong P, Kitisripanya T, Putalun W, Miyamoto T, Tanaka H, Morimoto S. Development of an indirect competitive immunochromatographic strip test for rapid detection and determination of anticancer drug, harringtonine.

J. Chromatogr. B Analyt Technol. Biomed. Life Sci. 1048: 150-4. 2017

 

Champy AS, Mitaine-Offer AC, Miyamoto T, Tanaka C, Papini AM, Lacaille-Dubois MA. Structural analysis of oleanane-type saponins from the roots of Wisteria frutescens.

Magn. Reson. Chem. 55: 595-600. 2017

 

Sakai M, Tujimura-Hayakawa T, Sur T, Yano H, Mitsushima M, Unoki-Kubota H, Kaburagi Y, Inoue H, Kido Y, Kasuga M, Matsumoto M.

The GCN5-CITED2-PKA signalling module controls hepatic glucose metabolism through a cAMP-induced substrate switch.

Nat. Commun. 7: 13147, 2016.

 

Passman AM, Low J, London R, Tirnitz-Parker JE, Miyajima A, Tanaka M, Strick-Marchand H, Darlington GJ, Finch-Edmondson M, Ochsner S, Zhu C, Whelan J, Callus BA, Yeoh GC.

A Transcriptomic Signature of Mouse Liver Progenitor Cells.

Stem Cells Int.2016: 5702873. 2016

 

Zhang P, Tsuchiya K, Kinoshita T, Kushiyama H, Suidasari S, Hatakeyama M, Imura H, Kato N, Suda T.

Vitamin B6 Prevents IL-1β Protein Production by Inhibiting NLRP3 Inflammasome Activation.

J. Biol. Chem. 291: 24517-27. 2016

 

Yoshikawa Y, Emi M, Hashimoto-Tamaoki T, Ohmuraya M, Sato A, Tsujimura T, Hasegawa S, Nakano T, Nasu M, Pastorino S, Szymiczek A, Bononi A, Tanji M, Pagano I, Gaudino G, Napolitano A, Goparaju C, Pass HI, Yang H, Carbone M.

High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma.

Proc. Natl. Acad. Sci. USA. 113: 13432-7. 2016

 

Kunii M, Ohara-Imaizumi M, Takahashi N, Kobayashi M, Kawakami R, Kondoh Y, Shimizu T, Simizu S, Lin B, Nunomura K, Aoyagi K, Ohno M, Ohmuraya M, Sato T, Yoshimura SI, Sato K, Harada R, Kim YJ, Osada H, Nemoto T, Kasai H, Kitamura T, Nagamatsu S, Harada A.

Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells.

J. Cell Biol. 215: 121-38. 2016

 

Hashimoto D, Chikamoto A, Taki K, Arima K, Yamashita Y, Ohmuraya M, Hirota M, Baba H.

Residual total pancreatectomy: Short- and long-term outcomes.

Pancreatology 16: 646-51. 2016

 

Watanabe Y, Honda S, Konishi A, Arakawa S, Murohashi M, Yamaguchi H, Torii S, Tanabe M, Tanaka S, Warabi E, Shimizu S.

Autophagy controls centrosome number by degrading Cep63.

Nat Commun. 7: 13508. 2016

 

Torii S, Yoshida T, Arakawa S, Honda S, Nakanishi A, Shimizu S. Identification

of PPM1D as an essential Ulk1 phosphatase for genotoxic stress-induced autophagy.

EMBO Rep. 17: 1552-64. 2016

 

Paudel MK, Sakamoto S, Huy LV, Tanaka H, Tomofumi M, Akihito T, Morimoto S.

Development of an immunoassay using an anti-wogonin glucuronide monoclonal antibody.

J. Immunoassay Immunochem. Dec 27. 2016

 

Ando J, Asanuma M, Dodo K, Yamakoshi H, Kawata S, Fujita K, Sodeoka M. Alkyne-tag SERS screening and identification of small-molecule-binding sites in protein.

J. Am. Chem. Soc. 138: 13901-10. 2016

 

Behler-Janbeck F, Takano T, Maus R, Stolper J, Jonigk D, Tort Tarrés M, Fuehner T, Prasse A, Welte T, Timmer MS, Stocker BL, Nakanishi Y, Miyamoto T, Yamasaki S, Maus UA.

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia.

PLoS Pathog. 12: e1006038. 2016

 

Iborra S, Martínez-López M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Izquierdo HM, Abram CL, Mori D, Campos-Martín Y, Reguera RM, Kemp B, Yamasaki S, Robinson MJ, Soto M, Lowell CA, Sancho D.

Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection.

Immunity 45:788-801. 2016

 

van der Peet PL, Nagata M, Shah S, White JM, Yamasaki S, Williams SJ.

Lipid structure influences the ability of glucose monocorynomycolate to signal through Mincle.

Org. Biomol. Chem. 14: 9267-77. 2016

 

Kimura Y, Inoue A, Hangai S, Saijo S, Negishi H, Nishio J, Yamasaki S, Iwakura Y, Yanai H, Taniguchi T. The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis.

Proc. Natl. Acad. Sci. USA. 113:14097-102. 2016

 

Zhou H, Yu M, Zhao J, Martin BN, Roychowdhury S, McMullen MR, Wang E, Fox PL, Yamasaki S, Nagy LE, Li X. IRAKM-Mincle axis links cell death to inflammation: Pathophysiological implications for chronic alcoholic liver disease.

Hepatology 64:1978-93. 2016

 

Clément M, Basatemur G, Masters L, Baker L, Bruneval P, Iwawaki T, Kneilling M, Yamasaki S, Goodall J, Mallat Z.

Necrotic Cell Sensor Clec4e Promotes a Proatherogenic Macrophage Phenotype Through Activation of the Unfolded Protein Response.

Circulation 134: 1039-51. 2016

 

Nojiri H, Miyagawa K, Banno S, Sakamoto I, Koike M, Sawa M, Iwase Y, Kudo H, Sakai T, Kaneko K.

Lumbar artery branches coursing vertically over the intervertebral discs of the lower lumbar spine: an anatomic study.

Eur. Spine J. 25: 4195-98. 2016

 

Tsuboyama K, Koyama-Honda I, Sakamaki Y, Koike M, Morishita H, Mizushima N.

The ATG conjugation systems are important for degradation of the inner autophagosomal membrane.

Science 354:1036-41. 2016

 

Yamanaka T, Tosaki A, Miyazaki H, Kurosawa M, Koike M, Uchiyama Y, Maity SN, Misawa H, Takahashi R, Shimogori T, Hattori N, Nukina N.

Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS.

Sci Rep. 6:34575. 2016

 

Honda Y, Otsuka A, Ono S, Yamamoto Y, Seidel JA, Morita S, Hirata M, Kataoka TR, Takenouchi T, Fujii K, Kanekura T, Okubo Y, Takahashi K, Yanagi T, Hoshina D, Hata H, Abe R, Fujimura T, Funakoshi T, Yoshino K, Masuzawa M, Amoh Y, Tanaka R, Fujisawa Y, Honda T, Kabashima K.

Infiltration of PD-1-positive cells in combination with tumor site PD-L1 expression is a positive prognostic factor in cutaneous angiosarcoma.

Oncoimmunology 6: e1253657. 2016

 

Shigehara Y, Okuda S, Nemer G, Chedraoui A, Hayashi R, Bitar F, Nakai H, Abbas O, Daou L, Abe R, Sleiman MB, Kibbi AG, Kurban M, Shimomura Y.

Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis.

Hum. Mol. Genet. 25: 4484-93. 2016

 

Shigehara Y, Okuda S, Nemer G, Chedraoui A, Hayashi R, Bitar F, Nakai H, Abbas O, Daou L, Abe R, Sleiman MB, Kibbi AG, Kurban M, Shimomura Y.

Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis.

Hum. Mol. Genet. Aug 18. 2016

 

Hayashi R, Abe R, Shimomura Y.

Expression studies of nectin-1 in human hair follicles and identification of a p63-responsive element in the NECTIN1 promoter.

J. Dermatol. Sci. 84: 221-4. 2016

 

Yamaguchi Y, Abe R, Haga N, Shimizu H.

A case of drug-associated dermatomyositis following ipilimumab therapy.

Eur. J. Dermatol. 26: 320-1. 2016

 

Ito T, Kohashi K, Yamada Y, Iwasaki T, Maekawa A, Kuda M, Hoshina D, Abe R, Furue M, Oda Y.

Prognostic Significance of Forkhead Box M1 (FOXM1) Expression and Antitumor Effect of FOXM1 Inhibition in Angiosarcoma.

J. Cancer. 7: 823-30. 2016

 

Hama N, Shimomura Y, Arinami H, Maruyama R, Abe R.

Localized heat urticaria: Positive reaction of preheated autologous serum skin test.

J. Dermatol. 43:1099-100. 2016

 

Shiba K, Abe R, Miyauchi T, Nomura T, Kondo T, Shimizu H.

Massive petechiae as an initial symptom of Waldenström’s macroglobulinemia.

Int. J. Dermatol. 55:e361-2. 2016

 

Tsurusaki S, Tahara-Hanaoka S, Shibagaki S, Miyake S, Imai M, Shibayama S, Kubo M, Shibuya A.

Allergin-1 inhibits TLR2-mediated mast cell activation and suppresses dermatitis.

Int. Immunol. 28:605-9. 2016

 

Udayanga KG, Nakamura Y, Nakahashi-Oda C, Shibuya A.

Immunoreceptor CD300a on mast cells and dendritic cells regulates neutrophil recruitment in a murine model of sepsis.

Int. Immunol. 28:611-5. 2016

 

Sato K, Honda SI, Shibuya A, Shibuya K.

Improved protocol for the isolation of naïve follicular dendritic cells.

Mol. Immunol. 78: 140-5. 2016

 

Kanaya M, Shibuya K, Hirochika R, Kanemoto M, Ohashi K, Okada M, Wagatsuma Y, Cho Y, Kojima H, Teshima T, Imamura M, Sakamaki H, Shibuya A.

Soluble DNAM-1, as a Predictive Biomarker for Acute Graft-Versus-Host Disease.

PLoS One 11: e0154173. 2016

 

Kuroda E, Ozasa K, Temizoz B, Ohata K, Koo CX, Kanuma T, Kusakabe T, Kobari S, Horie M, Morimoto Y, Nakajima S, Kabashima K, Ziegler SF, Iwakura Y, Ise W, Kurosaki T, Nagatake T, Kunisawa J, Takemura N, Uematsu S, Hayashi M, Aoshi T, Kobiyama K, Coban C, Ishii KJ.

Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation.

Immunity 45:1299-310. 2016

 

Goto Y, Uematsu S, Kiyono H.

Epithelial glycosylation in gut homeostasis and inflammation.

Nat. Immunol. 17: 1244-51. 2016

 

Imagawa Y, Saitoh T, Tsujimoto Y.

Vital staining for cell death identifies Atg9a-dependent necrosis in developmental bone formation in mouse.

Nat. Commun. 7: 13391. 2016

 

Maruyama K, Kawasaki T, Hamaguchi M, Hashimoto M, Furu M, Ito H, Fujii T, Takemura N, Karuppuchamy T, Kondo T, Kawasaki T, Fukasaka M, Misawa T, Saitoh T, Suzuki Y, Martino MM, Kumagai Y, Akira S.

Bone-protective Functions of Netrin 1 Protein.

J. Biol. Chem. 291: 23854-68. 2016

 

Santeford A, Wiley LA, Park S, Bamba S, Nakamura R, Gdoura A, Ferguson TA, Rao PK, Guan JL, Saitoh T, Akira S, Xavier R, Virgin HW 4th, Apte RS.

Impaired autophagy in macrophages promotes inflammatory eye disease.

Autophagy. 12: 1876-85. 2016

 

Isaka Y, Takabatake Y, Takahashi A, Saitoh T, Yoshimori T.

Hyperuricemia-induced inflammasome and kidney diseases.

Nephrol .Dial. Transplant. 31: 890-6. 2016

 

Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, Takeda K, Akira S. Pillars Article: Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the Lps Gene Product.

J. Immunol. 162: 3749-3752. 1999. J Immunol. 197: 2563-6. 2016

 

Ta HM, Le TM, Ishii H, Takarada-Iemata M, Hattori T, Hashida K, Yamamoto Y, Mori K, Takahashi R, Kitao Y, Hori O.

Atf6α deficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis.

J. Neurochem. 139:1124-37. 2016

 

Tanaka M, Miyajima A.

Liver regeneration and fibrosis after inflammation.

Inflammation and Regeneration, 2016

 

Toyonaga T, Torigoe S, Motomura Y, Kamichi T, Hayashi JM, Morita YS, Noguchi N, Chuma Y, Kiyohara H, Matsuo K, Tanaka H, Nakagawa Y, Sakuma T, Ohmuraya M, Yamamoto T, Umemura M, Mastuzaki G, Yoshikai Y, Yano I, Miyamoto T, Yamasaki S.

C-type lectin receptor DCAR recognizes mycobacterial phosphatidyl-inositol mannosides to promote a Th1 response during infection.

Immunity, 45:1245-57, 2016

 

Yamaguchi H, Arakawa S*(equally contribution), Kanaseki T, Miyatsuka T, Fujitani Y, Watada H, Tsujimoto Y, Shimizu S.

Golgi membrane-associated degradation pathway in yeast and mammals.

EMBO J. 35: 1991-2007, 2016

 

Shah S, Nagata M, Yamasaki S, Williams SJ.

Total synthesis of a cyclopropane-fatty acid α-glucosyl diglyceride from Lactobacillus plantarum and identification of its ability to signal through Mincle.

Chem Commun (Camb). 52: 10902-5. 2016

 

Ishikawa E, Kosako H, Yasuda T, Ohmuraya M, Araki K, Kurosaki T, Saito T, *Yamasaki S.

Protein kinase D regulates positive selection of CD4⁺ thymocytes through phosphorylation of SHP-1.

Nat. Commun. 7: 12756. 2016

 

Shibata K, Omahdi Z, Yamasaki S.

Necroptosis DAMPens anti-tumor immunity.

Cell Death Discovery, 2: 16033. 2016

 

Pastuhov SI, Fujiki K, Tsuge A, Asai K, Ishikawa S, Hirose K, Matsumoto K, Hisamoto, N.

The core molecular machinery used for engulfment of apoptotic cells regulates the JNK pathway mediating axon regeneration in Caenorhabditis elegans.

J. Neurosci. 36: 9710-21. 2016

 

Teponno RB, Tanaka C, Jie B, Tapondjou LA, Miyamoto T.

Trifasciatosides A–J, Steroidal Saponins from Sansevieria trifasciata Prain.

Chem Pharm Bull. 64: 1347-55. 2016

 

Sato S, Koike M, Funayama M, Ezaki J, Fukuda T, Ueno T, Uchiyama Y, Hattori N.

Lysosomal storage of subunit c of mitochondrial ATP synthase in brain-specific ATP13a2-deficient mice.

Am. J. Pathol. 186: 3074-82. 2016

 

Ounaissia K, Pertuit D, Mitaine-Offer AC, Miyamoto T, Tanaka C, Delemasure S, Dutartre P, Smati D, Lacaille-Dubois MA.

New pregnane and phenolic glycosides from Solenostemma argel.

Fitoterapia, 114: 98-104. 2016

 

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Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: Cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice.

Hum. Mol. Genet. 25: 3321-40. 2016

 

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Biochem. Biophys. Res. Commun. 480:23-8, 2016

 

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Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome.

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Detection of LacZ-Positive Cells in Living Tissue with Single-Cell Resolution.

Angew Chem Int Ed Engl. 55:9620-4, 2016

 

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Quantitative Proteomics-Based Reconstruction and Identification of Metabolic Pathways and Membrane Transport Proteins Related to Sugar Accumulation in Developing Fruits of Pear (Pyrus communis).

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Oncogene 35: 2407-12. 2016

 

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A Platinum-Catalyzed Friedel-Crafts-Type C–H Coupling–Allylic Amination Cascade to Synthesize 3,4-Fused Tricyclic Indoles.

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Central Insulin Action Activates Kupffer Cells by Suppressing Hepatic Vagal Activation via the Nicotinic Alpha 7 Acetylcholine Receptor.

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The P2X4 receptor is required for neuroprotection via ischemic preconditioning.

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TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis.

Nat. Commun. 7: 11379. 2016

 

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Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia.

Nature 532:117-21. 2016

 

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GATAe regulates intestinal stem cell maintenance and differentiation in Drosophila adult midgut.

Dev. Biol. 410: 24-35. 2016

 

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A specific tripeptidyl substrate for tripeptidyl peptidase activity is effectively hydrolyzed by alanyl aminopeptidase/aminopeptidase N/CD13 in the rat kidney.

Arch. Histol. Cytol. 76: 1-8. 2016

 

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PGAM5 deficiency confers resistance against metabolic stress in mice.

E Bio.Medicine 5: 82-92. 2016

 

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Lysosomal neutralization triggered by Zn2+ accumulation through ZnT2 inhibits autophagy.

Biochem. Biophys. Res. Commun. 471: 109-16. 2016

 

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Neuroprotection by selective neuronal deletion of autophagy-related gene ATG7 in neonatal brain injury.

Autophagy 12: 410-23. 2016

 

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Signalling through MyD88 drives surface expression of the mycobacterial　receptors MCL (Clecsf8, Clec4d) and Mincle (Clec4e) following microbial stimulation.

Microbes Infect. 18: 505-9. 2016

 

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Mycobacterial receptor, Clec4d (CLECSF8, MCL), is coregulated with Mincle and upregulated on mouse myeloid cells following microbial challenge.

Eur. J. Immunol. 46: 381-9. 2016

 

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Cycloartane-Type Saponins from Astragalus tmoleus var. tmoleus.

Nat. Prod. Commun. 11: 37-8. 2016

 

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Oleanolic acid and hederagenin glycosides from Weigela stelzneri.

Phytochemistry 123: 40-7. 2016

 

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Activation of murine invariant NKT cells promotes susceptibility to candidiasis by IL-10-induced modulation of phagocyte antifungal activity.

Eur. J. Immunol. 46: 1691-703. 2016

 

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Marginal zone B cells exacerbate endotoxic shock via interleukin-6 secretion induced by Fcα/μR-coupled TLR4 signalling.

Nat. Commun. 7: 11498. 2016

 

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Increased soluble CD155 in the serum of cancer patients.

PLoS ONE 11: e0152982. 2016

 

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Apoptotic epithelial cells control the abundance of Treg cells at barrier surfaces.

Nat. Immunol. 17: 441-50. 2016

 

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CD155/CD226-interaction impacts on the generation of innate CD8+ thymocytes by regulating iNKT-cell differentiation.

Eur. J. Immunol. 46: 993-1003. 2016

 

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Expression of DNAM-1 (CD226) on inflammatory monocytes.

Mol. Immunol, 69: 70-6. 2016

 

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p53 is a Host Cell Regulator during Herpes Simplex Encephalitis.

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Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.

Proc. Natl. Acad. Sci. U A. 113: E71-80. 2016

 

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Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice.

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The chaperone complex BAG2–HSC70 regulates localization of C. elegans Leucine-rich repeat kinase LRK-1 in the Golgi.

Genes to Cells 21: 311-24, 2016

 

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Regulation of the Inflammasomes by Autophagy.

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Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation.

Cell Host Microbe 19:91-101. 2016

 

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Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice.

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HECT-Type Ubiquitin E3 Ligase ITCH Interacts With Thioredoxin-Interacting Protein and Ameliorates Reactive Oxygen Species-Induced Cardiotoxicity.

J. Am. Heart Assoc. 5(1). 2016

 

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Subchronic inhalation exposure to 2-ethyl-1-hexanol impairs the mouse olfactory bulb via injury and subsequent repair of the nasal olfactory epithelium.

Arch Toxicol. 2016 Apr 8 [Epub ahead of print]

 

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Roles of Wnt Signaling in the Neurogenic Niche of the Adult Mouse Ventricular-Subventricular Zone.

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Deletion of Herpud1 Enhances Heme Oxygenase-1 Expression in a Mouse Model of Parkinson’s Disease.

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Deletion of Atf6α enhances kainate-induced neuronal death in mice.

Neurochem. Int. 92: 67-74. 2016

 

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Ectopic expression of myo-inositol 3-phosphate synthase induces a wide range of metabolic changes and confers salt tolerance in rice.

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Quantitative proteomics of Arabidopsis shoot microsomal proteins reveals a cross-talk between excess zinc and iron deficiency.

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Metabolic Profiling of Developing Pear Fruits Reveals Dynamic Variation in Primary and Secondary Metabolites, Including Plant Hormones.

PLoS One 10:e0131408, 2015

 

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NLRP3 mediates NF-κB activation and cytokine induction in microbially induced and sterile inflammation.

PLoS One 10:e0119179. 2015

 

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FLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIP.

Int. J. Mol. Sci. 16: 30321-41. 2015

 

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Successful surgical internal drainage of postoperative pancreatic pseudocyst through pancreaticojejunostomy with distal pancreatectomy: a case report.

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Cellular FLICE-Inhibitory Protein Regulates Tissue Homeostasis.

Curr. Top Microbiol. Immunol. 2015 Jul 10.

 

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Production of knockout mice by DNA microinjection of various CRISPR/Cas9 vectors into freeze-thawed fertilized oocytes.

BMC Biotechnol. 15: 33. 2015

 

Ida S, Ozaki N, Araki K, Hirashima K, Zaitsu Y, Taki K, Sakamoto Y, Miyamoto Y, Oki E, Morita M, Watanabe M, Maehara Y, Yamamura K, Baba H, Ohmuraya M.

SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-Associated Cancer.

Mol. Cancer Res. 13: 1130-8. 2015

 

Hashimoto D, Chikamoto A, Sakata K, Nakagawa S, Hayashi H, Ohmuraya M, Hirota M, Yoshida N, Beppu T, Baba H.

Staging laparoscopy leads to rapid induction of chemotherapy for unresectable pancreatobiliary cancers.

Asian J. Endosc. Surg. 8: 59-62. 2015

 

Hashimoto D, Chikamoto A, Ohmuraya M, Abe S, Nakagawa S, Beppu T, Takamori H, Hirota M, Baba H.

Impact of Postoperative Weight Loss on Survival After Resection for Pancreatic Cancer.

JPEN J. Parenter Enteral Nutr. 39:598-603. 2015

 

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Dual-Polarization Raman Spectral Imaging to Extract Overlapping Molecular Fingerprints of Living Cells.

J. Biophotonics, 8: 546-54. 2015

 

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VDAC3 gating is activated by suppression of disulfide-bond formation between the N-terminal region and the bottom of the pore.

Biochim. Biophys. Acta, 1848: 3188-96. 2015

 

Hayamizu K, Terayama N, Hashizume D, Dodo K, Sodeoka M. Unique features of chiral palladium enolates derived from β-ketoamide: Structure and catalytic asymmetric Michael and fluorination reactions.

Tetrahedron 71: 6594-601. 2015

 

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Photo-induced formation of cyclopropanols from α-ketoamides via γ-C-H bond activation.

Tetrahedron Lett. 56:5991-94. 2015

 

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Novel Raman-tagged sphingomyelin that closely mimics original raft-forming behavior.

Bioorg. Med. Chem. 23: 2989-94. 2015

 

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Mechanistic Study on A unique SN2’-type reaction of allylic alcohols with organolithium reagent accelerated by a proximal trifluoromethyl group.

J. Fluor. Chem., 179: 121-8. 2015

 

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Reactions of Carbonyl Compounds with Phosphorus Ylide Generated from Tribromofluoromethane and Tris(dimethylamino)phosphine.

Chem. Lett. 44: 1389-91. 2015

 

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Product Control in Alkene Trifluoromethylation: Hydro-trifluoromethylation, Vinylic Trifluoromethylation, and Iodo-trifluoromethylation Using Togni Reagent.

Chem. Asian J. 10: 2190-9. 2015

 

Kawamura S, Egami H, Sodeoka M.

Aminotrifluoromethylation of Olefins via Cyclic Amine Formation: Its Mechanistic Study and Application to Synthesis of Trifluoromethylated Pyrrolidines.

J. Am. Chem. Soc. 137: 4865-73. 2015

 

Ando J, Kinoshita M, Cui J, Yamakoshi H, Dodo K, Fujita K, Murata M, Sodeoka M.

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Proc. Nat. Acad. Sci.USA. 112: 4558-63. 2015

 

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Structure–activity relationships of benzhydrol derivatives based on 10-acetoxychavicol acetate (ACA) and their inhibitory activities on multiple myeloma cell growth via inactivation of the NF-kappaB pathway.

Bioorg. Med. Chem. 23: 2241-6. 2015

 

Lu S, Nishimura S, Hirai G, Ito M, Kawahara T, Izumikawa M, Sodeoka M, Shin-ya K, Tsuchida T, Kakeya H.

Saccharothriolides A-C, Novel Phenyl-substituted 10-Membered Macrolides from a Rare Actinomycete Saccharothrix sp.

Chem. Commun. 51: 8074-7. 2015

 

Hirai G, Sodeoka M.

Focused Library with Core Structure Extracted from Natural Products and Modified: Application to Phosphatase Inhibitors and Several Biochemical Findings.

Acc. Chem. Res. 48: 1464-73. 2015

 

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Biochem. Biophys. Res. Commun. 467: 1006-11. 2015

 

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Curr. Top Dev. Biol. 114: 159-84. 2015

 

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Dev. Cell 32:478-90. 2015

 

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Tyrosine-Specific Chemical Modification with in situ Hemin-Activated Luminol Derivatives.

ACS Chem. Biol. 10: 2633-40. 2015

 

Li G, Azuma S, Sato S, Minegishi H, Nakamura H.

ortho-Carboranylphenoxyacetanilides as Inhibitors of Hypoxia-Inducible Factor (HIF)-1Transcriptional Activity and Heat Shock Protein (HSP) 60 Chaperon Activity.

Bioorg. Med. Chem. Lett. 25: 2624-8. 2015

 

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Bioconjugate Chem. 26: 250-6. 2015

 

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Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c.

Proc. Natl. Acad .Sci. USA. 112: 8332-7. 2015

 

Matsuda T, Takahashi H, Mieda Y, Shimizu S, Kawamoto T, Matsuura Y, Takai T, Suzuki E, Kanno A, Koyanagi-Kimura M, Asahara S, Bartolome A, Yokoi N, Inoue H, Ogawa W, Seino S, Kido Y.

Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.

PLoS One 10: e0130757. 2015

 

Inaba Y, Furutani T, Kimura K, Watanabe H, Haga S, Kido Y, Matsumoto M, Yamamoto Y, Harada K, Kaneko S, Oyadomari S, Ozaki M, Kasuga M, Inoue H.

Growth arrest and DNA damage-inducible 34 regulates liver regeneration in hepatic steatosis in mice.

Hepatology 61:1343-56. 2015

 

Chalabi-Dchar M, Cassant-Sourdy S, Duluc C, Fanjul M, Lulka H, Samain R, Roche C, Breibach F, Delisle MB, Poupot M, Dufresne M, Shimaoka T, Yonehara S, Mathonnet M, Pyronnet S, Bousquet C.

Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.

Gastroenterology 148:1452-65. 2015

 

Lee Y, Sasai M, Ma JS, Sakaguchi N, Ohshima J, Bando H, Saitoh T, Akira S, Yamamoto M. p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.

Cell Rep. 13:223-33. 2015

 

Ohshima J, Sasai M, Liu J, Yamashita K, Ma JS, Lee Y, Bando H, Howard JC, Ebisu S, Hayashi M, Takeda K, Standley DM, Frickel EM, Yamamoto M.

RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.

Proc. Natl. Acad. Sci. USA. 112: E4581-90, 2015

 

Ito D, Nojima S, Nishide M, Okuno T, Takamatsu H, Kang S, Kimura T, Yoshida Y, Morimoto K, Maeda Y, Hosokawa T, Toyofuku T, Ohshima J, Kamimura D, Yamamoto M, Murakami M, Morii E, Rakugi H, Isaka Y, Kumanogoh A.

mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells

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Man SM, Karki R, Malireddi RK, Neale G, Vogel P, Yamamoto M, Lamkanfi M, Kanneganti TD. The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.

Nat. Immunol. 16: 467-75. 2015

 

Okumura T, Sasamura T, Inatomi M, Hozumi S, Nakamura M, Hatori R, Taniguchi K, Nakazawa N, Suzuki E, Maeda R, Yamakawa T, Matsuno K.

Class I myosins have overlapping and specialized functions in left-right asymmetric development in Drosophila.

Genetics 199: 1183-99. 2015

 

Sakai O, Uchida T, Roggia MF, Imai H, Ueta T, Amano S.

Role of Glutathione Peroxidase 4 in Glutamate-induced Oxytosis in the Retina.

PLoS One 10: e0130467. 2015

 

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J. Biochem. 158:127-37. 2015

 

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J. Virol. 90: 1677-81. 2015

 

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FEBS lett. 589: 1430-6. 2015

 

Rinchai D, Riyapa D, Buddhisa S, Utispan K, Titball RW, Stevens PM, Stevens JM, Ogawa M, Tanida I, Koike M, Uchiyama, Y., Ato, M., Lertmemongkolchai, G.

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Autophagy 11: 748-55. 2015

 

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Biomed. Res. 36: 121-33. 2015

 

Uemura N, Koike M, Asai K, Kinoshita M, Fujiwara-Ishikawa T, Matsui H, Naruse K, Sakamoto N, Uchiyama Y, Todo T, Takeda SI, Yamakado H, Takahashi R.

Viable neuronopathic Gaucher disease model in medaka (Oryzias latipes) displays axonal accumulation of alpha-synuclein.

Plos Genet. 11: e1005065. 2015.

 

Ichimura K, Miyazaki N, Sadayama S, Murata K, Koike M, Nakamura K, Ohta K, Sakai T.

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Sci. Rep. 5: 8993. 2015

 

Nori S, Okada Y, Nishimura S, Sasaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudoh J, Koike M, Uchiyama Y, Ikeda, E, Toyama Y, Nakamura M, Okano, H.

Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition. Stem.

Cell Rep. 4: 360-73. 2015

 

Asano, T, Koike M, Sakata S, Takeda Y, Nakagawa T, Hatano T, Ohashi S, Funayama M, Yoshimi K, Asanuma M, Toyokuni S, Mochizuki S, Uchiyama Y, Hattori N, Iwai K.

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Neurosci. Lett. 588: 29-35. 2015.

 

Ueno Y, Koike M, Shimada Y, Shimura H, Uchiyama Y, Hattori N, Urabe T.

L-carnitine enhances axonal plasticity and improves white-matter lesions after chronic hypoperfusion in rat brain.

J. Cereb. Blood Flow Metab. 35: 382-91. 2015

 

Tanaka M, Nishitai G.

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Curr. Top Microbiol. Immunol. 2015, Aug 18.

 

Motomura Y, Kanno S, Asano K, Tanaka M, Hasegawa Y, Katagiri H, Saito T, Hara H, Nishio H, Hara T, Yamasaki S.

Identification of Pathogenic Cardiac CD11c+ Macrophages in Nod1-Mediated Acute Coronary Arteritis.

Arterioscler Thromb Vasc Biol. 35: 1423-33. 2015

 

Inoue H, Matsuzaki Y, Tanaka A, Hosoi K, Ichimura K, Arasaki K, Wakana Y, Asano K, Tanaka M, Okuzaki D, Yamamoto A, Tani K, Tagaya M.

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Cell Sci. 128: 2781-94. 2015

 

Asano K, Takahashi N, Ushiki M, Monya M, Aihara F, Kuboki E, Moriyama S, Iida M, Kitamura H, Qiu CH, Watanabe T, Tanaka M.

Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes.

Nat. Commun.6: 7802. 2015

 

Kido T, Koui Y, Suzuki K, Kobayashi A, Miura Y, Chen EY, Tanaka M, Miyajima A.

CPM is a useful cell surface marker to isolate expandable bi-potential liver progenitor cells derived from human iPS cells.

Stem Cell Reports. 5:508-515 (2015)

 

Komori T, Tanaka M, Furuta H, Akamizu T, Miyajima A, Morikawa Y.

Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice.

Diabetologia. 58:1868-76. 2015

 

Guo S, Li ZZ, Gong J, Xiang M, Zhang P, Zhao GN, Li M, Zheng A, Zhu X, Lei H, Tanaka M, Li H.

Oncostatin M Confers Neuroprotection against Ischemic Stroke.

J. Neurosci. 35: 12047-62. 2015

 

Kurihara T, Arimochi H, Bhuyan ZA, Ishifune C, Tsumura H, Ito M, Ito Y, Kitamura A, Maekawa Y, Yasutomo K.

CD98 Heavy Chain Is a Potent Positive Regulator of CD4+ T Cell Proliferation and Interferon-γ Production In Vivo.

PLoS One 10: e0139692. 2015

 

Oh SJ, Ahn S, Jin YH, Ishifune C, Kim JH, Yasutomo K, Chung DH.

Notch 1 and Notch 2 synergistically regulate the differentiation and function of invariant NKT cells.

J. Leukoc. Biol. 98:781-9. 2015

 

Richardson MB, Torigoe S, Yamasaki S, Williams SJ.

Mycobacterium tuberculosis β-gentiobiosyl diacylglycerides signal through the pattern recognition receptor Mincle: total synthesis and structure activity relationships.

Chem. Commun. (Camb). 51: 15027-30. 2015

 

Kiyotake R, Oh-Hora M, Ishikawa E, Miyamoto T, Ishibashi T, Yamasaki S.

Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses.

J. Biol. Chem. 290: 25322-32. 2015

 

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C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation.

J. Immunol. 194:5366-74. 2015

 

van der Peet PL, Gunawan C, Torigoe S, Yamasaki S, Williams SJ.

Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle.

Chem. Commun. (Camb). 51: 5100-3. 2015

 

Nakamura Y, Sato K, Yamamoto H, Matsumura K, Matsumoto I, Nomura T, Miyasaka T, Ishii K, Kanno E, Tachi M, Yamasaki S, Saijo S, Iwakura Y, Kawakami K.

Dectin-2 deficiency promotes Th2 response and mucin production in the lungs after pulmonary infection with Cryptococcus neoformans.

Infect. Immun. 83: 671-81. 2015

 

Behler F, Maus R, Bohling J, Knippenberg S, Kirchhof G, Nagata M, Jonigk D, Izykowski N, Mägel L, Welte T, Yamasaki S, Maus UA.

Macrophage-inducible C-type lectin Mincle-expressing dendritic cells contribute to control of splenic Mycobacterium bovis BCG infection in mice.

Infect. Immun. 83: 184-96. 2015

 

Phongsisay V, Iizasa E, Hara H, Yamasaki S.

3-O-sulfo-β-D-galactose moiety of endogenous sulfoglycolipids is a potential ligand for immunoglobulin-like receptor LMIR5.

Mol. Immunol. 63: 595-9. 2015

 

Konoki K, Okada K, Kohama M, Matsuura H, Saito K, Cho Y, Nishitani G, MiyamotoT, Fukuzawa S, Tachibana K, Yotsu-Yamashita M.

Identification of okadaic acid binding protein 2 in reconstituted sponge cell clusters from Halichondria okadai and its contribution to the detoxification of okadaic acid.

Toxicon. 108: 38-45. 2015

 

Pertuit D, Mitaine-Offer AC, Miyamoto T, Tanaka C, Delemasure S, Dutartre P, Lacaille-Dubois MA.

A New Aromatic Compound from the Stem Bark of Terminaliacatappa.

Nat. Prod. Commun. 10: 1005-7. 2015

 

Rezgui A, Mitaine-Offer AC, Miyamoto T, Tanaka C, Lacaille-Dubois MA.

Spirostane-type saponins from Dracaena fragrans “Yellow Coast”.

Nat. Prod. Commun. 10:37-8. 2015

 

Aslan Erdem S, Mitaine-Offer AC, Miyamoto T, Kartal M, Lacaille-Dubois MA.

Triterpene saponins from Eryngium kotschyi.

Phytochemistry 110:160-5. 2015

 

Abe R.

Immunological response in Stevens-Johnson syndrome and toxic epidermal necrolysis.

J. Dermatol. 42: 42-8. 2015

 

Suda G, Yamamoto Y, Nagasaka A, Furuya K, Kudo M, Chuganji Y, Tsukuda Y, Tsunematsu S, Sato F, Terasita K, Nakai M, Horimoto H, Sho T, Natsuizaka M, Ogawa K, Ohnishi S, Chuma M, Fujita Y, Abe R, Taniguchi M, Nakagawa M, Asahina Y, Sakamoto N; NORTE Study Group.

Serum granulysin levels as a predictor of serious telaprevir-induced dermatological reactions.

Hepatol. Res. 45: 837-45. 2015

 

Aihara M, Kano Y, Fujita H, Kambara T, Matsukura S, Katayama I, Azukizawa H, Miyachi Y, Endo Y, Asada H, Miyagawa F, Morita E, Kaneko S, Abe R, Ochiai T, Sueki H, Watanabe H, Nagao K, Aoyama Y, Sayama K, Hashimoto K, Shiohara T; SJS/TEN Study Group.

Efficacy of additional i.v. immunoglobulin to steroid therapy in Stevens-Johnson syndrome and toxic epidermal necrolysis.

J. Dermatol. 42: 768-77. 2015

 

Kanemaru K, Noguchi E, Tokunaga T, Nagai K, Hiroyama T, Nakamura Y, Tahara-Hanaoka S, Shibuya A.

Tie2 Signaling Enhances Mast Cell Progenitor Adhesion to Vascular Cell Adhesion Molecule-1 (VCAM-1) through α4β1 Integrin.

PLoS One 10: e0144436. 2015

 

Weinstein JR, Quan Y, Hanson JF, Colonna L, Iorga M, Honda S, Shibuya K, Shibuya A, Elkon KB, M.ANvller T. IgM-Dependent Phagocytosis in Microglia Is Mediated by Complement Receptor 3, Not Fc.FNa/Nl Receptor.

J. Immunol. 195: 5309-17. 2015

 

Shibuya A, Honda S.

Immune regulation by Fcα/μ receptor (CD351) on marginal zone B cells and follicular dendritic cells.

Immunol Rev. 268: 288-95. 2015

 

Niizuma K, Tahara-Hanaoka S, Noguchi E, Shibuya A.

Identification and Characterization of CD300H, a New Member of the Human CD300 Immunoreceptor Family.

J. Biol. Chem. 290: 22298-308. 2015

 

Yamashita-Kanemaru Y, Takahashi Y, Wang Y, Tahara-Hanaoka S, Honda S, Bernhardt G, Shibuya A, Shibuya K.

CD155 (PVR/Necl5) Mediates a Costimulatory Signal in CD4+ T Cells and Regulates Allergic Inflammation.

J. Immunol. 194: 5644-53. 2015

 

Miki H, Nakahashi-Oda C, Sumida T, Shibuya A.

Involvement of CD300a Phosphatidylserine Immunoreceptor in Aluminum Salt Adjuvant-Induced Th2 Responses.

J. Immunol. 194: 5069-76. 2015

 

Takeshima K, Sato K, Nabekura T, Nagamune K, Hamada H, Yoshikawa H, Shibuya A, Shibuya K.

Increased CD11b+ Gr-1+ cell population in the placenta after infection with Toxoplasma gondii.

Microbiol Immunol. 59: 95-82015

 

Kurita N, Honda S, Shibuya A.

Increased serum IgA in Fcα/μR-deficient mice on the (129 x C57BL/6) F1 genetic background.

Mo. Immunol. 63: 367-72. 2015

 

Inada M, Takita M, Yokoyama S, Watanabe K, Tominari T, Matsumoto C, Hirata M, Maru Y, Maruyama T, Sugimoto Y, Narumiya S, Uematsu S, Akira S, Murphy G, Nagase H, Miyaura C.

Direct Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling That Drives Tumor Growth, Angiogenesis, and Metastasis.

J. Biol. Chem. 290:29781-93. 2015

 

Matsuda H, Hosono K, Tsuru S, Kurashige C, Sekiguchi K, Akira S, Uematsu S, Okamoto H, Majima M.

Roles of mPGES-1, an inducible prostaglandin E synthase, in enhancement of LPS-induced lymphangiogenesis in a mouse peritonitis model.

Life Sci. 142: 1-7. 2015

 

Flores-Langarica A, Bobat S, Marshall JL, Yam-Puc JC, Cook CN, Serre K, Kingsley RA, Flores-Romo L, Uematsu S, Akira S, Henderson IR, Toellner KM, Cunningham AF.

Soluble flagellin coimmunization attenuates Th1 priming to Salmonella and clearance by modulating dendritic cell activation and cytokineproduction.

Eur. J. Immunol. 45:2299-311. 2015

 

Maruyama K, Fukasaka M, Uematsu S, Takeuchi O, Kondo T, Saitoh T, Martino M, Akira S.

5-azacytidine-induced protein 2 (AZI2) regulates bone mass by fine-tuning osteoclast survival.

J. Biol. Chem. J. Biol. Chem. 290: 9377-862015

 

Atif SM, Lee SJ, Li LX, Uematsu S, Akira S, Gorjestani S, Lin X, Schweighoffer E, Tybulewicz VL, McSorley SJ.

Rapid CD4+ T-cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9.

Eur. J. Immunol. 45: 513-24. 2015

 

Kok CY, Miyajima A, Itoh T.

Adaptive remodeling of the biliary tree: the essence of liver progenitor cell expansion.

J. Hepatobiliary Pancreat. Sci. 22: 546-50. 2015

 

Kaneko K, Kamimoto K, Miyajima A, Itoh T.

Adaptive remodeling of the biliary architecture underlies liver homeostasis.

Hepatology 61: 2056-66. 2015

 

Ehara T, Kamei Y, Yuan X, Takahashi M, Kanai S, Tamura E, Tsujimoto K, Tamiya T, Nakagawa Y, Shimano H, Takai-Igarashi T, Hatada I, Suganami T, Hashimoto K, Ogawa Y.

Ligand-activated PPARα-dependent DNA demethylation regulates the fatty acid β-oxidation genes in the postnatal liver.

Diabetes 64: 775-84. 2015

 

Takagi M, Uno H, Nishi R, Sugimoto M, Hasegwa S, Piao J, Ihara N, Kanai S, Kakei S, Tamura Y, Suganami T, Kamei Y, Shimizu T, Yasuda A, Ogawa Y, Mizutani S.

ATM regulates adipocyte differentiation and contributes to glucose homeostasis.

Cell Reports 10: 957-67. 2015

 

Kobayashi S, Fukuhara A, Otsuki M, Suganami T, Ogawa Y, Morii E, Shimomura I.

Favine/CCDC3 is involved in lipid accumulation.

J. Biol. Chem. 290: 7443-51. 2015

 

Konuma K, Itoh M, Suganami T, Kanai S, Nakagawa N, Sakai T, Kawano H, Hara M, Kojima S, Izumi Y, Ogawa Y.

Eicosapentaenoic acid ameliorates non-alcoholic steatohepatitis in a novel mouse model using melanocortin 4 receptor-deficient mice.

PLoS One 10: e0121528. 2015

 

Murakami M, Yoshimoto T, Nakabayashi K, Tsuchiya K, Minami I, Bouchi R, Izumiyama H, Fujii Y, Abe K, Tayama C, Hashimoto K, Suganami T, Hata K, Kihara K, Ogawa Y.

Integration of transcriptome and methylome analysis of aldosterone-producing adenomas.

Eur. J. Endocrinol. 173: 185-95. 2015

 

Ogawa Y, Suganami T, Tanaka M, M. Itoh.

Parenchymal-stromal cell interaction in metabolic diseases.

Inflamm. Regen. 35: 167-71. 2015 (review)

 

Muramatsu-Kato K, *Itoh H, Kohmura-Kobayashi Y, Ferdous UJ, Tamura N, Yaguchi C, Uchida T, Suzuki K, Hashimoto K, Suganami T, Ogawa Y, Kanayama N.

Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress.

Sci Rep. 5: 16867. 2015

 

Li C, Hisamoto, N, Matsumoto K.

Axon regeneration is regulated by Ets–C/EBP transcription complexes generated by activation of the cAMP/Ca²⁺–p38 MAPK signaling pathways.

PLoS Genetics 11: e1005603. 2015

 

Pastuhov SI, Hisamoto, N, Matsumoto K.

MAP kinase cascades regulating axon regeneration in C. elegans.

Proc. Jpn. Acad. Ser. B. Phys. Biol. Sci. 91: 63-75. 2015

 

Shibutani ST, Saitoh T, Nowag H, Münz C, Yoshimori T.

Autophagy and autophagy-related proteins in the immune system.

Nat. Immunol. 16: 1014-24. 2015

 

Kojima T, Yamada T, Akaishi R, Furuta I, Saitoh T, Nakabayashi K, Nakayama KI, Nakayama K, Akira S, Minakami H.

Role of the Atg9a gene in intrauterine growth and survival of fetal mice.

Reprod. Biol. 15: 131-8. 2015

 

Misawa T, Saitoh T, Kozaki T, Park S, Takahama M, Akira S.

Resveratrol inhibits the acetylated α-tubulin-mediated assembly of the NLRP3-inflammasome.

Int. Immunol. 27: 425-34. 2015

 

Kozaki T, Takahama M, Misawa T, Matsuura Y, Akira S, Saitoh T.

Role of zinc-finger anti-viral protein in host defense against Sindbis virus.

Int. Immunol. 27: 357-64. 2015

 

Kumar S, Ingle H, Mishra S, Mahla RS, Kumar A, Kawai T, Akira S, Takaoka A, Raut AA, Kumar H.

IPS-1 differentially induces TRAIL, BCL2, BIRC3 and PRKCE in type I interferons-dependent and -independent anticancer activity.

Cell Death Dis. 6: e1758. 2015

 

Matsuda T, Murao N, Katano Y, Juliandi B, Kohyama J, Akira S, Kawai T, Nakashima K.

TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus.

Nat. Commun. 6: 6514. 2015

 

Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T.

Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B.

J. Biol. Chem. 290:1269-80. 2015

 

Nakatsu Y, Iwashita M, Sakoda H, Ono H, Nagata K, Matsunaga Y, Fukushima T, Fujishiro M, Kushiyama A, Kamata H, Takahashi S, Katagiri H, Honda H, Kiyonari H, Uchida T, Asano T.

Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit.

J. Biol. Chem. 290: 24255-66. 2015

 

Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Asano T.

DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.

Am. J. Physiol. Endocrinol. Metab. 309: E214-23. 2015

 

Nakatsu Y, Seno Y, Kushiyama A, Sakoda H, Fujishiro M, Katasako A, Mori K, Matsunaga Y, Fukushima T, Kanaoka R, Yamamotoya T, Kamata H, Asano T.

The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.

Am. J. Physiol. Gastrointest Liver Physiol. 309: G42-51. 2015

 

Fukushima T, Yoshihara H, Furuta H, Kamei H, Hakuno F, Luan J, Duan C, Saeki Y, Tanaka K, Iemura S, Natsume T, Chida K, Nakatsu Y, Kamata H, Asano T, Takahashi S.

Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.

Nat. Commun. 6: 6780. 2015

 

Okubo H, Nakatsu Y, Sakoda H, Kushiyama A, Fujishiro M, Fukushima T, Matsunaga Y, Ohno H, Yoneda M, Kamata H, Shinjo T, Iwashita M, Nishimura F, Asano T.

Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.

Am. J. Physiol. Gastrointest Liver Physiol. 308: G151-8. 2015

 

Qiang S, Nakatsu Y, Seno Y, Fujishiro M, Sakoda H, Kushiyama A, Mori K, Matsunaga Y, Yamamotoya T, Kamata H, Asano T.

Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus.

Diabetol. Metab. Syndr. 7: 104. 2015

 

Matsunaga Y, Nakatsu Y, Fukushima T, Okubo H, Iwashita M, Sakoda H, Fujishiro M, Yamamotoya T, Kushiyama A, Takahashi S, Tsuchiya Y, Kamata H, Tokunaga F, Iwai K, Asano T.

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.

Mediators Inflamm. 2015: 125380. 2015

 

Kanaoka R, Kushiyama A, Seno Y, Nakatsu Y, Matsunaga Y, Fukushima T, Tsuchiya Y, Sakoda H, Fujishiro M, Yamamotoya T, Kamata H, Matsubara A, Asano T.

Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.

PLoS One 10: e0127467. 2015

 

Ohba Y,Nakaya M, Watari K, Nagasaka A, Kurose H.

GRK6 phosphorylates IκBα at Ser(32)/Ser(36) and enhances TNF-α-induced inflammation.

Biochem. Biophys. Res. Commun. 461: 307-13. 2015

 

Tobo A, Tobo M, Nakakura T, Ebara M, Tomura H, Mogi C, Im DS, Murata N, Kuwabara A, Ito S, Fukuda H, Arisawa M, Shuto S, Nakaya M, Kurose H, Sato K, Okajima F.

Characterization of Imidazopyridine Compounds as Negative Allosteric Modulators of Proton-Sensing GPR4 in Extracellular Acidification-Induced Responses.

PLoS One 10: e0129334. 2015

 

Nagasaka A, Ohba Y, Kurose H, Nakaya M.

Novel functions of GRK6 in macrophages by phosphorylating the non-GPCRs substrates.

Macrophage 2: e1021. 2015

 

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Netrin-5 is highly expressed in neurogenic regions of the adult brain.

Front Cell Neurosci. 9: 146. 2015

 

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Sekiya T, Kondo T, Shichita T, Morita R, Ichinose H, Yoshimura A.

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Suzuki M, Morita R, Hirata Y, Shichita T, Yoshimura A.

Spred1, a Suppressor of the Ras-ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells.

J. Immunol. 195: 1273-81. 2015

 

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Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic Cells.

J. Immunity 43: 65-79. 2015

 

Ito M, Shichita T, Okada M, Komine R, Noguchi Y, Yoshimura A, Morita R.

Bruton’s tyrosine kinase (BTK) is an essential component for NLRP3 inflammasome activation and a potential therapeutic target for inflammation after ischemic brain injury.

Nat Commun. 6: 7360. 2015

 

Mi-ichi F, Miyamoto T, Takao S, Jeelani G, Hashimoto T, Hara H, Nozaki T, Yoshida H.

Entamoeba mitosomes play an important role in encystation by association with cholesteryl sulfate synthesis.

Proc. Natl. Acad. Sci. USA 112: E2884-90. 2015

 

Pertuit D, Lotfabad TB, Mitaine-Offer A-C, Miyamoto T, Tanaka C, M.-A. Lacaille-Dubois M-A.

Two new triterpene saponins from acanthophyllum laxiusculum.

Helvetica Chimica Acta, 98: 611-7. 2015

 

Gabriel AF, Li Z, Kusuda R, Tanaka C, Miyamoto T.

Six new polyacetylenic alcohols from the marine sponges Petrosia sp. and Halichondria sp.

Chem. Pharm. Bull. 63: 469-75. 2015

 

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The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity.

Cell Host Microbe. 17: 252-9. 2015

 

Yamakoshi H, Palonpon A, Dodo K, Ando J, Kawata S, Fujita K, Sodeoka M.

A sensitive and specific Raman probe based on bisarylbutadiyne for live cell imaging of mitochondria.

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Lauber S, Wong S, Cutz JC, Tanaka M, Barra N, Lhoták S, Ashkar A, Richards CD.

Novel function of Oncostatin M as a potent tumour-promoting agent in lung.

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Maekawa Y, Ishifune C, Tsukumo SI, Hozumi K, Yagita H, Yasutomo K.

Notch controls the survival of memory CD4+ T cells by regulating glucose uptake.

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Watanabe T, Ito T, Gouda H, Ishibashi Y, Miyamoto T, Ikeda K, Taguchi R, Okino N, Ito M.

Sterylglucoside catabolism in cryptococcus neoformans with endoglycoceramidase-related protein 2 (EGCrP2), the first steryl-beta-glucosidase identified in Fungi.

J. Biol. Chem. 290:1005-19. 2015

 

Kanno S, Nishio H, Tanaka T, Motomura Y, Murata K, Ihara K, Onimaru M, Yamasaki S, Kono H, Sueishi K, Hara T.

Activation of an innate immune receptor, nod1, accelerates atherogenesis in apoe-/- mice.

J. Immunol. 194:773-80. 2015

 

Karasawa K, Asano K, Moriyama S, Ushiki M, Monya M, Iida M, Kuboki E, Yagita H, Uchida K, Nitta K, Tanaka M.
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J. Am. Soc. Nephrol. 26: 896-906. 2015

 

Satou M, Enoki H, Oikawa A, Ohta D, Saito K, Hachiya T, Sakakibara H, Kusano M, Fukushima A, Saito K, Kobayashi M, Nagata N, Myouga F, Shinozaki K, Motohashi R.

Integrated analysis of transcriptome and metabolome of Arabidopsis albino or pale green mutants with disrupted nuclear-encoded chloroplast proteins.

Plant Mol Biol. 85:411-28, 2014

 

Tawaraya K, Horie R, Saito S, Wagatsuma T, Saito K, Oikawa A.

Metabolite Profiling of Root Exudates of Common Bean under Phosphorus Deficiency.

Metabolites. 4:599-611, 2014

 

Osanai T, Oikawa A, Iijima H, Kuwahara A, Asayama M, Tanaka K, Ikeuchi M, Saito K, Hirai MY.

Metabolomic analysis reveals rewiring of Synechocystis sp. PCC 6803 primary metabolism by ntcA overexpression.

Environ Microbiol. 16:3304-17, 2014

 

Doe K, Nozawa K, Hiruma K, Yamada Y, Matsuki Y, Nakano S, Ogasawara M, Nakano H, Ikeda T, Ikegami T, Fujishiro M, Kawasaki M, Ikeda K, Amano H, Morimoto S, Ogawa H, Takamori K, Sekigawa I, Takasaki Y.

Antibody against chromatin assembly factor-1 is a novel autoantibody specifically recognized in systemic lupus　erythematosus.

Lupus. 23: 1031-41. 2014

 

Egami H, Sodeoka M.

Recent progress on trifluoromethylation of alkenes with concomitant introduction of additional functional groups.

Angew. Chem. Int. Ed. 53: 8294-308. 2014

 

Sakuma C, Kawauchi T, Haraguchi S, Shikanai M, Yamaguchi Y, Gelfand VI, Luo L, Miura M, Chihara T.

Drosophila Strip serves as a platform for early endosome organization during axon elongation.

Nat. Commun. 5: 5180. 2014

 

Yamaguchi Y, Kuranaga E, Nakajima Y, Koto A, Takemoto K, Miura M.

In vivo monitoring of caspase activation using a fluorescence resonance energy transfer-based fluorescent probe.

Methods Enzymol. 544: 299-325. 2014

 

Miyajima A, Tanaka M, Itoh T.

Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming.

Cell Stem Cell 14: 561-74. 2014 Review.

 

Tanaka M, Ikeda K, Suganami T, Komiya C, Ochi K, Shirakawa I, Hamaguchi M, Nishimura S, Manabe I, Matsuda T, Kimura K, Inoue H, Inagaki Y, Aoe S, Yamasaki S, Ogawa Y.

Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis.

Nat. Commun. 5: 4982. 2014

 

Kawai Y, Ouchida R, Yamasaki S, Dragone L, Tsubata T, Wang JY.

LAPTM5 promotes lysosomal degradation of intracellular CD3ζ but not of cell surface CD3ζ.

Immunol. Cell Biol. 92: 527-34. 2014

 

Sato F, Miyaoka Y, Miyajima A, Tanaka M.

Oncostatin M maintains the hematopoietic microenvironment in the bone marrow by modulating adipogenesis and osteogenesis.

PLoS One 9: e116209. 2014

 

Egami H, Shimizu R, Usui Y, Sodeoka M.

Oxy-trifluoromethylation of alkenes and its application to the synthesis of β-trifluoromethylstyrene derivatives.

J. Fluor. Chem. 167: 172-8. 2014

 

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Am. Surg. 80: 1212-5. 2014

 

Kusuda T, Nakashima Y, Murata K, Kanno S, Nishio H, Tanaka T, Yamamura K, Sakai Y, Takada H, Hara T, Saito M, Miyamoto T, Mizuno Y, Ouchi K, Waki K.

Kawasaki disease-specific molecules in the sera are linked to microbe-associated molecular patterns in the biofilms.

PLoS One 9: 113054. 2014

 

Thuaud F, Kojima S, Hirai G, Oonuma K, Tsuchiya A, Uchida T, Tsuchimoto T, Sodeoka M.

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Bioorg. Med. Chem. 22: 2771-82. 2014

 

Kitamura A, Sasaki A, Abe T, Kano H, Yasutomo K.

An inherited mutation in NLRC4 causes autoinflammation in human and mice.

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Yonekawa A, Saijo S, Hoshino Y, Miyake Y, Ishikawa E, Suzukawa M, Inoue H, Tanaka M, Yoneyama M, Oh‐hora M, Akashi K, Yamasaki S.
Dectin‐2 is a direct receptor for mannose‐capped lipoarabinomannan of mycobacteria.
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Ishibashi Y, Nagamatsu Y, Miyamoto T, Matsunaga N, Okino N, Yamaguchi K, Ito M.
A novel ether‐linked phytol‐containing digalactosylglycerolipid in the marine green alga, Ulva pertusa.
Biochem. Biophys. Res. Commun. 452:873-80. 2014

 

Tabopda TK, Mitaine‐Offer AC, Tanaka C, Miyamoto T, Mirjolet JF, Duchamp O, Ngadjui BT, Lacaille‐Dubois MA.
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Egami H, Ide T, Fujita M, Tojo T, Hamashima Y, Sodeoka M.
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Sodeoka M, Egami H.
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J. Am. Soc. Nephrol. 25:1680‐1697. 2014

 

Liu T, Yamaguchi Y, Shirasaki Y, Shikada K, Yamagishi M, Hoshino K, Kaisho T, Takemoto K, Suzuki T, Kuranaga E, Ohara O, Miura M.
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Shimazu T, Barjau J, Sohtome Y, Sodeoka M, Shinkai Y.
Selenium‐Based S‐Adenosylmethionine Analog Reveals the Mammalian Seven‐Beta‐Strand Methyltransferase METTL10 to Be an EF1A1 Lysine Methyltransferase.
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Yagai T, Miyajima A, Tanaka M.
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Miyamoto T, Okimoto T, Kuwano M.
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Ohgane K, Karaki F, Noguchi‐Yachide T, Dodo K, Hashimoto Y.
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Yamaguchi T, Asanuma M, Nakanishi S, Saito Y, Okazaki M, Dodo K, Sodeoka M.
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Giordano M, Roncagalli R, Bourdely P, ChassonL, Buferne M, Yamasaki S, Beyaert R, van Loo G, Auphan‐Anezin N, Schmitt‐Verhulst AM, Verdeil G.
The tumor necrosis factor alpha‐induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells.
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Karaki F, Ohgane K, Fukuda H, Nakamura M, Dodo K, Hashimoto Y.
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Phongsisay V, Iizasa E, Hara H, Yamasaki S.
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Hashimoto D, Chikamoto A, Ohmuraya M, Sakata K, Miyake K, Kuroki H, Watanabe M, Beppu T, Hirota M, Baba H.
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Surg. Today 44: 1313‐20. 2014

 

Hashimoto D, Chikamoto A, Ohmuraya M, Hirota M, Baba H.
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Miyazaki A, Asanuma M, Dodo K, Egami H, Sodeoka M.
A “catch‐and‐release” protocol for alkyne‐tagged molecules based on a resin‐bound cobalt complex for peptide enrichment in aqueous media.
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Pertuit D, Avunduk S, Mitaine‐Offer AC, Miyamoto T, Tanaka C, Paululat T, Delemasure S, Dutartre P, Lacaille‐Dubois MA.
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Phytochemistry 102:182‐8. 2014

 

Honda S, Arakawa S, Nishida Y, Yamaguchi H, Ishii E, Shimizu S.
Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.
Nature Commun. 5:4004. 2014

 

Hattori Y, Morita D, Fujiwara N, Mori D, Nakamura T, Harashima H, Yamasaki S, Sugita M.
Glycerol monomycolate is a novel ligand for the human, but not mouse macrophage inducible C‐type lectin, mincle.
J. Biol. Chem. 289:15405‐12. 2014

 

Nagashima H, Okuyama Y, Asao A, Kawabe T, Yamaki S, Nakano H, Croft M, Ishii I, So T.
The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL‐6.
Nat. Immunol. 15:449‐56. 2014

 

Komori T, Tanaka M, Senba E, Miyajima A, Morikawa Y.
Deficiency of Oncostatin M receptor b (OSMRβ) exacerbates high‐fat diet‐induced obesity and related metabolic disorders in mice.
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Thuaud F. Kojima S. Hirai G. Onnuma K, Tsuchiya A, Uchida T, Tsuchimoto T, Sodeoka M.
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Manase MJ, Mitaine‐Offer AC, Miyamoto T, Tanaka C, Delemasure S, Dutartre P, Lacaille‐Dubois MA.
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Ishifune C, Maruyama S, Sasaki Y, Yagita H, Hozumi K, Tomita T, Kishihara K, Yasutomo K.
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Roncagalli R, Hauri S, Fiore F, Liang Y, Chen Z, Sansoni A, Kanduri K, Joly R, Malzac A, Lahdemaki H, Lahesmaa R, Yamasaki S, Saito T, Mallisen M, Aebersold R, Gstaiger M, Malissen B.
Quantitative proteomic analysis of signalosome dynamics in primary T cells identifies the CD6 surface receptor as a LAT‐independent TCR signaling hub.
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Ravishankar B, Shinde R, Liu H, Chaudhary K, Bradley J, Lemos HP, Chandler P, Tanaka M, Munn DH, Mellor AL, McGaha TL.
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Ozaki N, Fukuchi Y, Tomiyoshi S R, Uehara H, Ida S, Wang J, Araki K, Sibilia M, Baba H, Yamamura K, Ohmuraya M.
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Biochem. Biophys. Res. Commun. 446: 224‐30. 2014

 

Nakagawa Y, Sakuma T, Nakagata N, Yamasaki S, Takeda N, Ohmuraya M, Yamamoto T.
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Exp. Anim. 63: 349‐55. 2014

 

Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, Yamamoto M.
Nrf2 enhances cholangiocyte expansion in Pten‐deficient livers.
Mol. Cell. Biol. 34:900‐13. 2014

 

Bhuyan ZA, Asanoma M, Iwata A, Ishifune C, Maekawa Y, Shimada M, Yasutomo K.
Abrogation of Rbpj attenuates experimental autoimmune uveoretinitis by inhibiting IL‐22‐producing CD4+ T cells.
PLoS One 9:e89266. 2014

 

Yamakoshi H, Phlonpon AF, Dodo K, Ando J, Kawata S, Fujita K, Sodeoka M.
Simultaneous imaging of protonated and deprotonated carbonylcyanide p‐trifluoromethoxyphenylhydrazone in live cells by Raman microscopy.
Chem. Commun. 50:1341‐3. 2014

 

Toyonaga K, Miyake Y, Yamasaki S.
Characterization of the Receptors for Mycobacterial Cord Factor in Guinea Pig.
PLoS One 9:e88747. 2014.

 

Bian Z, Dai J, Nakano H, Guan H, Yuan Y, Gan L, Zhou H, Zong J, Zhang Y, F. F, Yan L, Shen D, Li H, Tang Q.
Disuption of Tumor Necrosis Factor Receptor Associated Factor 5 Exacerbates Pressure Overload Cardiac Hypertrophy and Fibrosis.
J. Cell. Biochem. 115:349‐58. 2014

 

Nakagawa Y, Yamamoto T, Suzuki K, Araki K, Takeda N, Ohmuraya M, Sakuma T.
Screening methods to identify TALEN‐mediated knockout mice.
Exp. Anim. 63: 79‐84. 2014

 

Ashour A, El‐Sharkawy S, Amer M, Abdel Bar F, Katakura Y, Miyamoto T, Toyota N, Bang TH, Kondo R, Shimizu K.
Rational design and synthesis of topoisomerase I and II inhibitors based on oleanolic acid moiety for new anti‐cancer drugs.
Bioorg Med Chem. 22: 211‐20.2014

 

Sakata K, Ohmuraya M, Araki K, Suzuki C, Ida S, Hashimoto D, Wang J, Uchiyama Y, Baba H, Yamamura K.
Generation and analysis of serine protease inhibitor kazal type 3‐cre driver mice.
Exp. Anim. 63: 45‐53. 2014